Month: May 2020

In HER2-positive breast cancer patients with brain metastases treated with trastuzumab and capecitabine, add-on tucatinib increased median overall survival from 12 months to 18.1 months in a phase 2 trial. The results were presented as part of the American Society of Clinical Oncology virtual scientific program and published simultaneously in the Journal of Clinical Oncology.
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Print this page KENILWORTH, N.J. & MIAMI–(BUSINESS WIRE) May 26, 2020 –Merck (NYSE: MRK), known as MSD outside the United States and Canada, and Ridgeback Biotherapeutics LP, a closely held biotechnology company, today announced that the companies have entered into a collaboration agreement to develop EIDD-2801, an orally available antiviral candidate currently in early clinical
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Some patients aged 80 or older can potentially cut back on their number of antihypertensive meds, under physician guidance, without an important loss of blood pressure (BP) control, conclude researchers based on their randomized multicenter trial. Deprescription of 1 of at least 2 antihypertensive meds in such patients was found noninferior to usual care in
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Acoustic neuroma, also known as vestibular schwannoma, is a noncancerous and usually slow-growing tumor that develops on the main (vestibular) nerve leading from your inner ear to your brain. Branches of this nerve directly influence your balance and hearing, and pressure from an acoustic neuroma can cause hearing loss, ringing in your ear and unsteadiness.
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Print this page NORTHBROOK, Ill., May 27, 2020 /PRNewswire/ — Astellas Pharma Inc. (TSE: 4503, President and CEO: Kenji Yasukawa, Ph.D., “Astellas”) announced today that the U.S. Food and Drug Administration (FDA) has approved VESIcare LS (solifenacin succinate) oral suspension for the treatment of neurogenic detrusor overactivity (NDO) in pediatric patients aged 2 years and
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Androgen-deprivation therapy (ADT) with an oral gonadotropin-releasing hormone (GnRH) antagonist rapidly suppressed testosterone and cut the incidence of serious heart events compared to an injectable form of ADT, a phase III trial found. The so-called HERO study of over 900 patients met its primary endpoint, demonstrating that castration at 48 weeks was maintained in 96.7%
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Zucchini is popular among people with diabetes for a good reason. For every 100 g of this vegetable, you get loads of vitamins and minerals, and just 3.11g of carbs, 1g of which is dietary fiber!  Now summer is just around the corner, which means we can enjoy in-season produce zucchini soon. The next few
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Cailin Healy, and an unidentified friend, both of Calabasas, take a selfie together as beach-goers enjoy warm summer-like weather amid state and city social distancing regulations mandated by Gov. Newsom in Huntinton Beach, CA, on April 22, 2020. Allen J. Schaben | Los Angeles Times via Getty Images As the U.S. begins to reemerge from
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Here are the coronavirus stories Medscape’s editors around the globe think you need to know about today: Social Distancing Flattened the Curve, Studies Say  Two new modeling studies indicate that social distancing interventions flattened the curve of COVID-19 hospitalizations compared with
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White blood cell. Credit: EM Unit Malaria drug used to treat glioblastoma  One of the most aggressive types of brain cancer could be treated with an already approved malaria drug. Lumefantrine has been proposed in combination with the current  care/treatments – to treat patients with glioblastoma.  This type of brain cancer has a poor survival
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Reviewed by Emily Henderson, B.Sc.May 29 2020 Cameron Nowzari, Assistant Professor, Electrical and Computer Engineering, received $150,000 from the National Science Foundation for a project in which he and his collaborators are developing numerical methods and mathematical models to provide complementary support to the epidemiologists worldwide who are working to understand how COVID-19 spreads. Some
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Prescription fills for hydroxychloroquine/chloroquine spiked right after COVID-19 was declared a national emergency in March, but use of the drugs still remains well above 2019 levels, based on data from more than 58,000 U.S. pharmacies. Hydroxychloroquine/chloroquine are also doing better than
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At least 1,721,750 people have been infected with coronavirus in the US and 101,617 have died, according to data from Johns Hopkins University. The US Centers for Disease Control and Prevention projects that by June 20 the death toll will reach about 123,000. The projection is based on an ensemble forecast of more than a
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The Prevention TaskForce app (formerly ePSS) is an application designed and developed by the Agency for Healthcare Research and Quality (AHRQ), the nation’s lead federal agency for research on healthcare quality, costs, outcomes, and patient safety. It was developed by AHRQ to support the independent U.S. Preventive Services Task Force. We previously reviewed ePSS (electronic
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Living with diabetes comes with many challenges; we need to constantly know what and how much we eat and drink, and continuously calibrate our medications, like metformin or insulin, accordingly. It can be exhausting. One shining beacon of light (and a delicious thirst-quencher) is diet soda. It’s sweet, it’s refreshing, and it has zero carbohydrates! But
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U.S. President Donald Trump speaks to reporters after he received a 2020 hurricane season briefing during the coronavirus disease (COVID-19) outbreak in Washington, May 28, 2020. Jonathan Ernst | Reuters President Donald Trump announced Friday that the United States will cut ties with the World Health Organization. “China has total control over the World Health
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