London, UK — 16 January 2021 GlaxoSmithKline (GSK) plc announced updated data from GARNET cohort F evaluating dostarlimab in mismatch repair-deficient (dMMR) non-endometrial advanced solid cancers being presented today at the 2021 American Society of Clinical Oncology Gastrointestinal Cancers Symposium (ASCO GI). Study results (abstract #9) showed a 38.7% objective response rate (ORR) (N=106, 95% CI;
Month: January 2021
WASHINGTON – The director of the Centers for Disease Control and Prevention warned Sunday that the federal government does not know how much coronavirus vaccine the nation has, a complication that adds to the already herculean task before the Biden administration. “I can’t tell you how much vaccine we have, and if I can’t tell it
Advancements in diabetes technology have improved quality of life and glycemic control in children with type 1 diabetes. However, data show that a subset of children is being left behind. Those from low-income families and non-Hispanic Black (NHB) children are not experiencing benefits associated with technological advances, and are at higher risk for diabetes complications
“If you hear hoofbeats, you are more likely to see a horse, unless you are in an evolving COVID-19 pandemic. Then it may be a zebra.” — Benji Mathews, MD, of Regions Hospital in St. Paul, Minnesota, on including atypical COVID-19 manifestations in a differential diagnosis. “These are the very hard realities that essential workers
Musician, documentary maker, and entrepreneur, Stephen Manderson – AKA Professor Green – has never shied away from difficult subjects. In this candid chat, he opens up about echo chambers, activism, and his journey with gut health Stephen Manderson became a prolific voice in the mental health conversation when he released his first documentary in 2015,
The presence of ischemia on stress testing should not be used to refer patients with ischemic cardiomyopathy for coronary artery bypass graft (CABG) surgery, a new STICH analysis concludes. Previously, the Surgical Treatment for Ischemic Heart Failure (STICH) trial showed that CABG plus medical therapy provided no mortality benefit over medical therapy at 5 years,
Carina Lawson, founder of eco-friendly planner brand Ponderlily, knows how hard it can be to make time for wellbeing, which is why she’s helping people create space for meaning and a life of fullness, rather than busyness How many times has Sunday evening rolled around, and you’ve promised yourself you’re going to make a dentist
Dr John Bartlett John G. Bartlett, MD, professor emeritus at the Johns Hopkins University School of Medicine and a prominent leader and instructor in infectious disease medicine, died January 19 at age 83. The cause of death was not immediately disclosed. Bartlett is remembered by colleagues for his wide range of infectious disease expertise, an
This content originally appeared on Low Carb Yum. Republished with permission. Ketchup is an important part of so many classic American foods. Who doesn’t enjoy this condiment with their hot dogs, burgers, or fries? Before I was eating low carb, I used to love these meals! Now, I’m much more conscious about the impact that
Patients with acute myeloid leukemia (AML), the most common form of acute leukemia in adults, that has gone into remission following initial chemotherapy remain in remission longer and have improved overall survival when they are given a pill form of the cancer drug azacitidine as a maintenance treatment, according to a randomized, international phase 3
U.S. President Joe Biden speaks about his administration’s plans to respond to the economic crisis during a coronavirus disease (COVID-19) response event in the State Dining Room at the White House in Washington, January 22, 2021. Jonathan Ernst | Reuters President Joe Biden has painted a bleak picture of the nation’s coronavirus outbreak in his
Many college students fully recover from infectious mononucleosis (which is almost always caused by Epstein-Barr virus) within 1-6 weeks, but some go on to develop chronic fatigue syndrome, also called myalgic encephalomyelitis (ME/CFS). A longitudinal study from DePaul University and Northwestern University followed 4,501 college students to examine risk factors that may trigger longer illness.
Low doses of the recombinant T-cell growth factor interleukin 2 (IL-2, aldesleukin, Proleukin) were well tolerated among patients with moderate-to-severe ulcerative colitis in a small 8-week study, with only one patient being withdrawn because of a dose-limiting toxicity, a researcher reported. There also were preliminary suggestions of efficacy, with 38.4% of the 26 patients enrolled
High breast density has been linked to a potentially increased risk of breast cancer, and it can also make cancer harder to detect on a mammogram. However, a new study suggests that people with low breast density may not actually have the better lot in life after all. The study, published in JAMA Network Open,
Researchers have developed a new classification of cognitive function for patients with multiple sclerosis (MS) that is based on the identification of five cognitive phenotypes. Dr Ermelinda De Meo “This is the first time there has been a complete categorization of cognitive profiles in MS patients,” lead author Ermelinda De Meo, MD, IRCCS San Raffaele
What is it that makes us, us? Here we explore the role our memories play – and what happens when they’re taken from us Recently, I got around to watching Pixar’s Inside Out, an animation depicting the emotions and inner workings of the mind of an 11-year-old girl as her family moves to a new
Rodney Gabel, Binghamton University, State University of New York President Joe Biden called for American unity after four years of political divisiveness and the “raging fire” it provoked. He promised to be a president for all Americans. “I will fight as hard for those who did not support me as for those who did,” he
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Full-dose anticoagulation was superior to low, prophylactic doses in reducing the need for vital organ support such as ventilation in moderately ill patients hospitalized for COVID-19, according to a report released today by the National Institutes of Health (NIH). “This is
As many of us continue to stay at home more than usual, finding new ways to make creative, easy and healthy dinners is a priority for many. Recently, I tried out a meal kit delivery service from Gobble and thought I would share my thoughts as a mom of two living with type 1 diabetes.
New York and Mainz, Germany, January 20, 2021 — Today, Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) announced results from an in vitro study that provides additional data on the capability of sera from individuals immunized with the Pfizer-BioNTech COVID-19 vaccine BNT162b2 to neutralize the SARS-CoV-2 U.K. strain, also known as B.1.1.7 lineage or VOC 202012/01. The results were published
FDA Approves Cabenuva (cabotegravir and rilpivirine) Long-Acting Injectable HIV Treatment and Vocabria (cabotegravir) Oral HIV Treatment London, 21 January 2021 – ViiV Healthcare, the global specialist HIV company majority owned by GlaxoSmithKline plc (“GSK”), with Pfizer Inc. and Shionogi Limited as shareholders, today announced that the US Food and Drug Administration (FDA) approved Cabenuva, the first
Walgreens Pharmacist Jessica Sahni holds the Pfizer-BioNTech coronavirus disease (COVID-19) vaccine at The New Jewish Home in New York, December 21, 2020. Yuki Iwamura | Reuters Pfizer said it had fully enrolled its Covid-19 vaccine trial in kids ages 12 to 15, a key step before the vaccine could be used in that age group.
A new peer-reviewed study reveals that the vast majority of U.S. infants may be suffering from a substantial deficiency in an important bacterium key to breast milk utilization and immune system development, as well as protection against gut pathogens linked to common newborn conditions such as colic and diaper rash. According to the study published
Ten cases of anaphylaxis and over 100 cases of severe allergic reactions were reported following administration of the first dose of the Moderna COVID-19 vaccine, but nearly all were among those with a history of allergic reactions, researchers found. Of the 10 cases of anaphylaxis, nine were among those with a history of allergies or
Blood tests to screen for amyloid-beta could cut the need for PET scans in half in asymptomatic Alzheimer’s research trials, a British cohort study suggested. To find 100 amyloid PET-positive, dementia-free older adults from a population with similar amyloid PET positivity prevalence to the study cohort without plasma screening, 543 PET scans would need to
Getting cancer treatment is draining, both physically and mentally. One woman battling breast cancer decided to put a positive spin on her situation by doing one random act of kindness during each of her recent 33 radiation treatments. That got her a spot on an NHL roster… an honorary one, anyway. Angelique Fong is a
And bad moods are more contagious than good moods, researchers have found If you live alongside a teenager, or ever were one yourself, the latest findings from the Universities of Birmingham and Oxford may not come as a huge surprise to you, as they discovered that teenagers can ‘catch’ moods from their friends – and
In a study published by JAMA Psychiatry methamphetamine overdose deaths rose dramatically over an eight-year period from 2011-2018. The study, conducted by the National Institute on Drug Abuse, determined that while the country was focused on the opioid crisis, a methamphetamine crisis was developing “quietly and actively.” The death rate from methamphetamine overdoses rose from
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