Month: February 2021

22 February 2021 — AstraZeneca today announced the voluntary withdrawal of the Imfinzi (durvalumab) indication in the US for previously treated adult patients with locally advanced or metastatic bladder cancer. This decision was made in consultation with the Food and Drug Administration (FDA). In May 2017, Imfinzi was granted accelerated approval in the US based on promising
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FDA Approves Amondys 45 (casimersen) Injection for the Treatment of Duchenne Muscular Dystrophy (DMD) in Patients Amenable to Skipping Exon 45 CAMBRIDGE, Mass., Feb. 25, 2021 (GLOBE NEWSWIRE) —  Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, today announced that the U.S. Food and Drug Administration (FDA) has approved Amondys
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A general view of the Centers for Disease Control and Prevention (CDC) headquarters in Atlanta. Tami Chappell | Reuters A new CDC study found that some elderly who apparently recovered from the coronavirus later came down with a second, even worse infection — indicating that asymptomatic or mild cases may not provide a lot of
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Ahead of Rare Disease Day (28 February), four leading children’s research institutions on three continents are joining forces to decipher pediatric illnesses, including rare diseases, and find better treatments. The four pediatric hospitals — Boston Children’s Hospital; UCL Great Ormond Street Institute for Child Health and Great Ormond Street Hospital (London); the Murdoch Children’s Research
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Multisystem inflammatory syndrome in children (MIS-C) has seen a surge in cases trailing the winter wave of COVID-19 in adults, but the treatment and recognition of it are better than in the earlier waves, clinicians and researchers say. Over the last 30 days, there have been around 11 cases of this SARS-CoV-2 infection-linked syndrome at
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Formal exams have been cancelled in favour of teacher-led assessments The coronavirus pandemic has impacted the education system in a big way, with various attempts made by the government to soften the blow to those taking exams. Last year, the approach was described by many as chaotic as a controversial algorithm was initially used to
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Two research teams have identified a new coronavirus variant in New York City and across the Northeast that could evade natural immune responses and some monoclonal antibody treatments, according to CNN. The variant, called B.1.526, has appeared in diverse neighborhoods in
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In December, the Supreme Court reversed a lower court ruling that had allowed abortion medications to be sent by mail. Since then, women looking to terminate a pregnancy with the combination medications packet containing mifepristone and misoprostol now must go, in person, to a medical provider. But this in-person requirement is not necessary in many
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maralixibat Treatment for Cholestatic Pruritus in Patients with Alagille Syndrome Mirum Pharmaceuticals Announces Completion of Rolling NDA Submission for Maralixibat in Alagille Syndrome FOSTER CITY, Calif.–(BUSINESS WIRE)–Feb. 1, 2021– Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) today announced it has completed submission of its rolling New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for maralixibat for the
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Dr. Peter Hotez told CNBC’s “The News with Shepard Smith” that people in the U.S. should not become complacent because of dropping Covid cases, especially amid new reports of a new variant, B.1.526, spreading in New York. “We’re all high fiving ourselves because the numbers are going down, and I am saying that we are
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Adding an immunomodulator to standard R-CHOP therapy failed to improve progression-free survival in high-risk diffuse large B-cell lymphoma (DLBCL), an international randomized trial showed. Although median progression-free survival (PFS) had yet to be reached, the trial did not meet the prespecified 37.5% reduction in hazard ratio (HR) with R-CHOP plus lenalidomide (Revlimid, R2-CHOP). Instead, adding
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The path to becoming a doctor is challenging. First college as a pre-med, then medical school, and finally residency. Which part is the most challenging? In this video we’ll go over each stage. Vlog channel: https://youtube.com/lifeofasurgeon Pre-med Roadmap to Med School Acceptance: https://medschoolinsiders.com/all-courses/ College vs Medical School: https://youtu.be/PgHotL0MOVM Med School vs Residency: https://youtu.be/3mFF8It-oG8 My Struggles
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Results showing once-weekly subcutaneous semaglutide, as an adjunct to intensive behavioral therapy and an initial low calorie diet, induced weight loss that was 10.3% greater compared with placebo over 68 weeks in people with obesity or overweight, were published today in JAMA. The findings, from the phase 3, randomized, double-blind STEP 3 study for the
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Professor Willie Hamilton specialises in primary care diagnostics at the University of Exeter. Comment and opinion from Cancer Research UK’s community of experts. The opinions outlined in this article do not necessarily represent the views of Cancer Research UK. The original cancer problem was that we weren’t testing smartly enough. When I became a GP
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NEW BRUNSWICK, N.J., February 19, 2021– Johnson & Johnson (NYSE: JNJ) (the Company) announced that Janssen-Cilag International N.V. has submitted for Emergency Use Listing (EUL) to the World Health Organization (WHO) for the investigational single-dose Janssen COVID-19 vaccine candidate. The data package delivered today includes interim efficacy and safety results from the Phase 3 ENSEMBLE clinical
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