Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in
Month: February 2023
Boxes of mifepristone, the first pill given in a medical abortion, are prepared for patients at Women’s Reproductive Clinic of New Mexico in Santa Teresa, U.S., January 13, 2023. Evelyn Hockstein | Reuters A coalition of a dozen Democratic attorneys general sued the Food and Drug Administration on Friday to force the agency to drop
Peanut sublingual immunotherapy (SLIT) achieved clinically significant desensitization to peanut allergens in the majority of children in an open-label, prospective study. Among 47 kids who completed therapy and the 48-month double-blind, placebo-controlled food challenge, 70% achieved clinically significant desensitization (successfully consumed dose [SCD] >800 mg), and 36% achieved full desensitization (SCD 5,000 mg), reported Edwin
This video is part of an ongoing series of interviews with government leaders in healthcare. In this video, Jeremy Faust, MD, editor-in-chief of MedPage Today, and Ashish Jha, MD, MPH, the White House COVID-19 Response Coordinator for the Biden administration, discuss the end of the COVID-19 public health emergency (PHE) in May and what that
Label expansion for Cibinqo provides new systemic oral option for adolescents (12 to <18 years) with moderate-to-severe atopic dermatitis NEW YORK–(BUSINESS WIRE) February 10, 2023 — Pfizer Inc. (NYSE: PFE) announced today that the United States (U.S.) Food and Drug Administration (FDA) approved its supplemental New Drug Application (sNDA) for Cibinqo® (abrocitinib), expanding its indication
Here are the main differences between medical school and residency. In medical school, you’re in school. You’re a student paying tuition to earn your medical degree. During the first two years, you’ll primarily learn in the classroom through didactics and small groups. During the last two years, you’ll be on your clinical rotations and learn
SAN DIEGO — Cognitive behavioral therapy (CBT), the wakefulness-promoting drug modafinil (Provigil), and a combination of both treatments all reduce fatigue in patients with multiple sclerosis (MS) — but the combination has an edge when it comes to overall perceived benefits, new research shows. As well, the results suggest that individuals with poorer sleep hygiene
We’ve gathered together some positive news from the past month to break through the noise and show you there’s good in the world 1. Write on time Two transatlantic pen pals, who have been messaging since 1938, celebrated their 100th birthdays with their first video call. The milestone moment saw the lifelong friends, Geoff from
Oil pulling has become a popular dental practice in recent years, thanks to TikTok. But does the practice have any real difference to the pearly whites? Oil pulling requires swishing a tablespoon of edible oil in the mouth for 5 to 10 minutes, or up to 20. It is based on the principle that the method “pulls”
Sign up for CNN’s Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more. CNN — Astronomers have used the James Webb Space Telescope to peer back in time to the early days of the universe — and they spotted something unexpected. The space observatory revealed six massive galaxies
©Shutterstock Vaccinations (vaccines) have been a game changer in the medical world and human health. They’ve helped protect us from measles and mumps, polio, and most recently COVID-19. They’ve even eradicated smallpox, one of the deadliest diseases in human history. Can they do something similar for cancer? Many vaccines are made from weakened or harmless
Emily Shares How She Lost 50 Pounds with Type 1 Diabetes – Diabetes Daily Learning Center Learning Center: LearningCenter Diabetes Daily does not provide medical advice,diagnosis or treatment.Get additional information.© 2005 – 2023 Everyday Health, Inc., a Ziff Davis company. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not
HONOLULU — In the clinical experience of April W. Armstrong, MD, MPH, topical therapies typically don’t work well for nail psoriasis, so she sometimes resorts to intralesional injections combined with systemic therapy. One might think of intralesional injections “as a torture method from the medieval days,” she said at the Hawaii Dermatology Seminar provided by MedscapeLIVE!, but intramatricial corticosteroid
Many COVID-19 trackers are shutting down in light of the public health emergency ending in May. But experts are worried that the closing of trackers might negatively impact pandemic management. Generally, COVID trackers detail information like the number of cases, hospitalizations, and deaths as well as state-wise or district-wise distribution of cases. The end of
Researchers from the University of Queensland have identified that a gene associated with an increased risk of Parkinson’s Disease also contributes to a build-up of cell debris in the brain. Dr Adekunle Bademosi from The Queensland Brain Institute said the discovery could change the focus of Parkinson’s Disease treatment. Our team has found that a
Scientists have wondered whether boys and girls think differently because their brains are different. A recent paper presents evidence that, indeed, girls do show meaningful differences in their brain circuits that could explain why their cognitive functions differ from those of boys. Study: Measures of Brain Connectivity and Cognition by Sex in US Children. Image
The Alzheimer’s drug LEQEMBI is seen in this undated handout image obtained by Reuters on January 20, 2023. Eisai | via Reuters Medicare will not provide broader coverage of the Alzheimer’s drug Leqembi until it receives more evidence that the treatment is reasonable and necessary, according to the federal agency that runs the program for
The recent news cycle has focused on the tragic deaths of three young children in Boston, allegedly at the hands of their mother. Lindsay Clancy, a labor and delivery nurse, has been charged with homicide in the killings of her 8-month-old, 3-year-old, and 5-year-old children. It is believed that after she strangled them, she injured
Conversion from accelerated to regular (full) approval based on long-term outcomes from the GARNET phase I trial, which demonstrated an overall response rate of 45.4% 85.9% of patients had duration of response ≥12 months and 54.7% of patients had duration of response ≥24 months London, UK — 10 February 2023 — GSK plc (LSE/NYSE: GSK)
For people with postural orthostatic tachycardia syndrome (POTS), everyday tasks can be daunting. Symptoms such as fatigue, dizziness and stomach problems greatly impact quality of life. Patients with POTS may look healthy, but they say they feel terrible, making it hard for other people to understand. In this Mayo Clinic Minute, reporter Vivien Williams talks
Gastroenterologists in 2023 will have more tools in their arsenal to treat patients with Crohn’s disease or ulcerative colitis. As many as 8-10 adalimumab biosimilars are anticipated to come on the market this year, giving mainstay drug Humira some vigorous competition. Dr Edward Oldfield Three scenarios will drive adalimumab biosimilar initiation: Insurance preference for the
With almost one in two carers stating that the cost of living is having a negative effect on their mental health, we take a closer look and highlight the support that’s available New findings from Surewise.com reveal that nearly one in two carers agree that the current economic crisis is negatively impacting their mental health,
There has been a rise in back pain problems in recent times. Hours of sitting at a desk can often lead to such issues, which highlight the complications of a sedentary lifestyle. Luckily for us, scientists have found the perfect combination of drugs that can alleviate back pain. In the study, published in the Journal of
Sign up for CNN’s Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more. CNN — Archaeologists digging in a cave in southern France say they have unearthed the earliest evidence of bow and arrow use outside Africa. Grotte Mandrin, near Malataverne in the Rhône Valley, is a cave
The Diabetes Advice That Made a Difference – Diabetes Daily Learning Center Learning Center: LearningCenter Diabetes Daily does not provide medical advice,diagnosis or treatment.Get additional information.© 2005 – 2023 Everyday Health, Inc., a Ziff Davis company. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third
Cold snare polypectomy (CSP) is superior to hot snare polypectomy (HSP) for colorectal polyps measuring 4-10 mm, a pragmatic randomized controlled trial confirms. In the Taiwan Cold Polypectomy Study, CSP was not only safer than HSP, with a significantly lower risk for delayed bleeding, it was also more efficient, report Li-Chun Chang, MD, PhD, from
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