Allergies & Asthma

The FDA approved a pressured, metered-dose inhaler containing albuterol and budesonide (Airsupra) for treating adults with asthma, drugmaker AstraZeneca announced. The combination, formerly known as PT027, is specifically indicated for the as-needed treatment or prevention of bronchoconstriction and to reduce the risk of exacerbations in adults with asthma, and is the first product containing both
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While there was no association between prenatal exposure to acid-suppressive medications and allergic diseases in kids, infant exposure was linked to a higher risk of developing asthma, a South Korean nationwide cohort study showed. Among over 84,000 pairs of infants exposed and unexposed to proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs), the
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In this video, MedPage Today editor-in-chief Jeremy Faust, MD, sits down with allergist and immunologist Zachary Rubin, MD, of Oak Brook Allergists in Illinois, to discuss the lasting affects of COVID-19 on pediatric health. Part one of their discussion — where they discuss the pediatric “tripledemic” of flu, respiratory syncytial virus (RSV), and COVID-19 —
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After suffering allergy season after allergy season, many people will offer their best piece of advice for managing your symptoms. One common recommendation is nasal sprays. This blog dives into how nasal sprays work, how they’re different than oral antihistamines, and how disease-modifying treatment can help reduce the need for symptom relievers over time. How
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Dupilumab (Dupixent) was superior to placebo in the phase III trial underpinning its approval last spring for eosinophilic esophagitis (EoE), researchers said. About 60% of patients receiving the active drug — a monoclonal antibody targeting interleukin (IL) types 4 and 13 — achieved histologic remission, compared with just 5%-6% assigned to placebo in the multi-part
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Among patients with chronic obstructive pulmonary disease (COPD) and severe chronic breathlessness, short-term daily treatment with low doses of extended-release morphine did not significantly reduce the intensity of worst breathlessness, a randomized trial showed. At 1 week, change in the intensity of worst breathlessness was not significantly different between patients who received 8 mg/day of
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LOUISVILLE, Ky. — An investigational fixed-dose combination of a short-acting beta2-adrenergic agonist and an inhaled corticosteroid appeared to slow the deterioration in lung function and reduce severe exacerbations for patients with mild-to-moderate asthma, according to an exploratory analysis of a phase III trial. Among the nearly 1,000 patients in the DENALI trial, those in the
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LOUISVILLE, Ky. — A sublingual film may be able to deliver epinephrine as effectively as intramuscular injections and provide an alternate pathway for urgent treatment of allergic anaphylaxis, a researcher suggested here. In testing with healthy volunteers, the sublingual film loaded with AQST-109, which delivers 12 mg of epinephrine, appeared to have similar pharmacokinetics as
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LOUISVILLE, Ky. — Treatment with add-on dupilumab (Dupixent) was linked with clinically meaningful improvements in hives and itch severity in patients with chronic spontaneous urticaria (CSU), according to the LIBERTY-CSU CUPID Study A trial. In patients as young as 6 years with itch and hives that were not adequately controlled on antihistamine treatment alone, dupilumab
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