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Atopic dermatitis (AD) monotherapy with the lebrikizumab, an interleukin-13 inhibitor, was shown to be both effective and safe in the induction periods of the phase 3 ADvocate1 and ADvocate2 trials, researchers reported in the New England Journal of Medicine. The identically designed, 52-week, randomized, double-blind, placebo-controlled trials enrolled 851 adolescents and adults with moderate to severe AD and included
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Higher blood caffeine levels appear to reduce the risks for both adiposity and type 2 diabetes, the results of a new study suggest. Explaining that caffeine has thermogenic effects, the researchers note that previous short-term studies have linked caffeine intake with reductions in weight and fat mass. And observational data have shown associations between coffee
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Scientists have identified rare damaging gene variants associated with an increased risk of schizophrenia.  The multi-center study led by the Icahn School of Medicine at Mount Sinai found the schizophrenia risk from these rare damaging variants is conserved across ethnicities, NeuroScienceNews reported.  The study, published in the journal Nature Genetics, may open up new treatment strategies.
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Black patients with pulmonary fibrosis (PF) consistently experienced poor outcomes associated with their disease at earlier ages than other groups, including hospitalization and death, according to U.S. registry data spanning nearly two decades. In an analysis from the Pulmonary Fibrosis Foundation Registry (PFFR) from 2003 to 2021, a PF diagnosis in Black individuals occurred about
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Despite their convenience and low cost, handheld point-of-care (POC) devices lack precision for measuring neonatal bilirubin and need refinement in order to tailor jaundice management in newborns, a systematic review and meta-analysis reports in JAMA Pediatrics. Lauren E.H. Westenberg, MD, of the division of neonatology at Erasmus MC Sophia Children’s Hospital in Rotterdam, the Netherlands, and colleagues
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A trailblazing new study has helped develop a blood test to find a person’s risk of developing anxiety, as well as its current severity. The test can also predict if a person is likely to get more anxious in the future and how other factors, such as changes in hormones, might influence anxiety. After being
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“You don’t see the sun. You don’t smell the flowers.” — Oleksandr Rikhter, MD, a top trauma physician from Ukraine, on the day-to-day lives of healthcare workers after the country was invaded by Russia. “Even asking one question routinely — how do you manage your stress? — can be very helpful for patients to open
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Former National Football League players who had symptoms of concussion during their careers showed poorer performance on cognitive testing, compared with nonplayers, new research shows. “Our results suggest that cognitive impacts of football-related concussion can be really long-lasting and these impacts may be coming from both concussive and subconcussive injury — that is, even head
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Of all the consequences of climate change, here’s one nobody counted on. A team of European researchers digging into Siberian permafrost discovered and revived 13 types of prehistoric viruses. As the ancient frozen ground slowly loses its “perma” label due to rising temperatures, more and more microbes that have never encountered modern humans are resurfacing. The
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For the first time in the U.S., a medical case of tickborne illness caused by an unexpected species of bacteria has been reported, as per the Centers for Disease Control and Prevention (CDC).  The bacteria called Borrelia lonestari is a distant relative of the bacteria responsible for Lyme disease. The pathogen was found responsible for triggering tickborne
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For prostate cancers detected by screening, cancer-specific mortality was low at 15-year follow-up regardless of whether patients underwent active monitoring, prostatectomy, or radiotherapy, results from the phase III randomized ProtecT study showed. Among over 1,600 men from the U.K. with prostate cancers detected by a prostate-specific antigen (PSA) test, death from their malignancy occurred in
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A year before the COVID-19 pandemic began, a team of clinical statisticians at the University of Texas MD Anderson Cancer Center sat together in small office for a year, painstakingly hand coding data from the US clinical trials database, www.clinicaltrials.gov. They were trying to answer a simple question: Why are cancer-drug trials enrolling too few
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Another expert has spoken out amid the weight-loss trend involving Ozempic and similar drugs fueled by reports about Hollywood celebrities crediting them for their body transformation.  Dr. Thomas Su, a plastic surgeon, exclusively spoke with Us Weekly to address the worrying trend that caused shortages amid the strong demand for Ozempic, Wegovy and similar drugs. 
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It’s Oscars weekend, so for our 2nd annual Meddy Awards — our very self-congratulatory and very tongue-in-cheek version of the Oscars — we celebrate outstanding medical performances and events in motion pictures throughout history. Without further ado (or comedy skits or musical numbers or extended tributes or commercials), the Meddys go to… Best Depiction of
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Josh struggled for more than a decade with what his doctors had told him was irritable bowel syndrome (IBS). But curiously, the 39-year-old’s flare-ups were caused by some foods that aren’t typical IBS triggers. Peanuts and shellfish caused “stabbing” abdominal pains, and he would feel lightheaded after simply inhaling the scent of them. He also
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