‘The Evil Hand Is Mother Nature’: What We Heard This Week

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“The evil hand is mother nature.” — Paul Offit, MD, of Children’s Hospital of Philadelphia, explaining why Pfizer’s mRNA vaccine work is not gain-of-function research.

“We’ve been doing a lot more amputations over the last couple of years for really bad necrotic wounds and dysfunctional limbs and infections that go all the way down to the bone.” — Joseph D’Orazio, MD, of Temple University Hospital in Philadelphia, on managing wounds related to xylazine-laced fentanyl.

“It’s a relatively narrow window.” — Megan Patrick, PhD, of the University of Michigan in Ann Arbor, on how high school students can easily go from drinking for the first time to heavy binging.

“The point that is often lost in biological and medical research is that race is not the stressor or the factor, structural racism is.” — Matthew Edwards, MD, of Stanford University School of Medicine in California, on study showing lower gray matter volume in key brain regions in Black children compared with white children.

“Our findings raise questions about systemic changes in continuity in medication use.” — Puneet Kaur Chehal, PhD, of Emory University in Atlanta, on a study finding one in five adults with diabetes didn’t keep up with their glucose-lowering medication.

“The effects of vigorous, regular exercise have been poorly studied.” — Davangere Devanand, MD, of Columbia University Irving Medical Center in New York City, on how this type of exercise might have slowed disease progression in two patients with positive Alzheimer’s biomarkers and mild cognitive impairment.

“I’m concerned that this class-wide scheduling approach sets a precedent of guilty until proven innocent.” — Rep. Tony Cárdenas (D-Calif.), during a House subcommittee discussion about classifying all fentanyl-like substances as Schedule 1 controlled substances and the implications of mandatory minimum sentencing for drug offenses.

“People are going to be pretty shocked when things like [nirmatrelvir-ritonavir] Paxlovid are no longer free.” — Jeffrey Levi, PhD, of George Washington University in Washington, D.C., on the Biden administration’s plans to end the COVID-19 public health emergency in May.

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