Month: April 2021

Lowering blood pressure with antihypertensive medication protects against future cardiovascular (CV) events even in people with normal or only mildly elevated blood pressure, a large meta-analysis concludes. Results showed that each 5 mm Hg reduction in systolic blood pressure lowered the relative risk for CV events by about 10% across the full spectrum of baseline
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CAMBRIDGE, Mass., April 28, 2021 /PRNewswire/ – Akebia Therapeutics, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today announced that the New England Journal of Medicine (NEJM) has published the results of the global Phase 3 clinical program of vadadustat for the treatment of anemia due to chronic kidney disease
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bardoxolone Treatment for Alport Syndrome Reata Announces FDA Accepted for Filing the NDA for Bardoxolone for the Treatment of Patients With Chronic Kidney Disease Caused by Alport Syndrome PLANO, Texas, April 26, 2021 (GLOBE NEWSWIRE) — Reata Pharmaceuticals, Inc. (Nasdaq: RETA) (“Reata,” the “Company,” or “we”), a clinical-stage biopharmaceutical company, today announced that the U.S.
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Fitness technology no longer sits on your laptop, tablet or phone.  Now it’s even…something you wear, thanks to wearable fitness technology gadgets. On a recent morning, Malvina Abbott, 78, a public defender in San Diego, was in her apartment catching up on emails, and the time got away from her. That’s when her Galaxy smart
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Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus–a region of the brain tied to memory and learning. Such detailed mapping, made possible
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Contents of baby’s first stool were a biomarker for early-life allergy risk in a study of 100 infants. Infants who developed IgE-mediated atopy by age 1 showed a significantly poorer environment in their meconium — the fecal matter accumulated prior to birth and typically expelled within a few days of delivery — for microbiotal development
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Patients with neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE) seem to benefit from rituximab (Rituxan) therapy, according to data from the British Isles Lupus Assessment Group Biologics Register (BILAG-BR). Indeed, the percentage of patients with active disease, as scored by the BILAG-2004 index or SLEDAI-2K (SLE Disease Activity Index 2000), fell significantly (P < .0001) when
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. People who experience particular side effects after receiving a COVID-19 vaccine, such as swollen lymph nodes, may have previously been infected with the coronavirus, according to a new study published on the medRxiv preprint server. The study hasn’t yet been peer-reviewed.
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A team of scientists from A-Alpha Bio., USA, has recently conducted a large-scale screening of 33 therapeutic antibodies to examine their binding affinity to a number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The team analyzed the impact of potential mutations in the spike receptor-binding domain (RBD) on antibody efficacy. The study is
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mobocertinib Treatment for Non-Small Cell Lung Cancer Takeda Announces U.S. FDA Grants Priority Review for New Drug Application for Mobocertinib (TAK-788) as a Treatment for EGFR Exon20 Insertion+ Metastatic Non-Small Cell Lung Cancer CAMBRIDGE, Mass. & OSAKA, Japan–(BUSINESS WIRE) April 27, 2021– Takeda Pharmaceutical Company Limited (TSE:4502/NYSE:TAK) (“Takeda”) today announced that the U.S. Food and
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People wearing face masks as a precaution walking along Orchard Road, a famous shopping district in Singapore. Maverick Asio | SOPA Images | LightRocket | Getty Images SINGAPORE — Singapore’s health ministry reported 16 new locally transmitted coronavirus cases on Thursday, the highest number since July 11, 2020, when the country reported 24 community cases.
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After more than a year of the coronavirus disease 2019 (COVID-19) pandemic, it has become clear that children are less susceptible to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), both in terms of the number of infections and the severity of illness. However, some children do develop severe disease as well as a host
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Psychiatrist Tami Benton, MD, had a 5-year-old patient threaten to run into traffic to end her life. When Benton asked the girl what she thought would happen after she died, the girl replied, “‘I will come back tomorrow, and I’ll be a good girl, and my parents will be happy again.'” The child’s parents lost
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When my kids were little, we began a little ritual of putting something in our pockets each day. You see, we had moved about 950 miles from where our kids had lived all of their young lives. Everything was different. Weather. Accents. Scenery. There was understandable sadness in missing their home and friends. There was
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The Centers for Disease Control and Prevention (CDC) is finalizing new guidelines to help clinicians diagnose and manage long COVID, or post-acute sequelae of SARS-CoV2 infection. In a daylong congressional hearing on Thursday, John Brooks, MD, a medical epidemiologist at the
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A study that warned of the perils of using face masks as a precaution against contracting Covid-19 appears slated for retraction, Retraction Watch has learned. The 2020 paper, “Facemasks in the COVID-19 era: A health hypothesis,” was written by Baruch Vainshelboim,
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NESS ZIONA, Israel, April 27, 2021 (GLOBE NEWSWIRE) — Sol-Gel Technologies, Ltd. (NASDAQ: SLGL), a clinical-stage dermatology company focused on identifying, developing and commercializing branded and generic topical drug products for the treatment of skin diseases, today announced an update regarding the U.S. Food and Drug Administration (FDA) approval process for Epsolay (benzoyl peroxide) 5%
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