Clinical Trials & Research

During her 12-hour overnight shift, Brianna Shelton helps residents at BeeHive Homes Assisted Living go to the bathroom. Many of them have dementia, and some can’t get out of bed on their own. Only a few can remember her name, but that doesn’t matter to her. “They’re somebody’s mom, somebody’s grandma, somebody’s great-grandmother,” Shelton said.
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In low- and middle-income countries (LMICs), breast cancer poses an urgent crisis, but most countries lack proper medical imaging equipment to assess the breast. A new PLOS Digital Health pilot study evaluated the efficacy of the volume sweep imaging (VSI) ultrasound scans and artificial intelligence (Samsung S-Detect for Breast) in providing fully automated and inexpensive breast ultrasound
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Cephalopods like octopuses, squids and cuttlefish are highly intelligent animals with complex nervous systems. In “Science Advances”, a team led by Nikolaus Rajewsky of the Max Delbrück Center has now shown that their evolution is linked to a dramatic expansion of their microRNA repertoire. If we go far enough back in evolutionary history, we encounter
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe acute respiratory syndrome coronavirus (SARS-CoV) are members of the subgenus Sarbecovirus, whose genomic length is around 30,000 base pairs. These viruses encode four structural proteins, namely spike (S), envelope (E), membrane (M), and nucleocapsid (N). Study: Recombination-aware phylogenetic analysis sheds light on the evolutionary origin of
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Sino Biological, Inc. (“Sino Biological” or the “Company”), a biotechnology company listed on the Shenzhen stock exchange subsidiary ChiNext (SZSE: 301047), which provides biological research reagents and related technical contract research services, is pleased to announce the formal signing of a lease with Hines and initiation of construction on its new Center for Bioprocessing (C4B)
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In a recent study posted to the bioRxiv* preprint server, researchers evaluated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure among rats inhabiting New York City (NYC) during the fall of 2021. Study: SARS-CoV-2 exposure in Norwegian rats (Rattus norvegicus) from New York City. Image Credit: Wirestock Creators/Shutterstock Background Studies have reported that SARS-CoV-2 VOCs
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From Ziath LtdNov 22 2022Reviewed by Maria Osipova Rapid 2D barcode rack readers and automated tube picking equipment from Ziath are helping Colorifix (Norwich, UK) to accelerate development of revolutionary biological dyes to help the textile industry dramatically reduce its environmental impact. Image Credit: Ziath Ltd Dyeing of fabrics by the textile industry represents one
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In a recent study published in Frontiers in Immunology, researchers assessed the efficacy of chimeric antigen receptor (CAR) T-cells in the immunotherapy of colorectal cancer (CRC). Study: CAR T-cells for colorectal cancer immunotherapy: Ready to go? Image Credit: Meletios Verras/Shutterstock Background CAR T-cells are a novel cell-based immunotherapy against cancer that is developed genetically. The
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In a recent study published in the Emerging Infectious Disease Journal, researchers detected a swine influenza A virus (IAV)-infected patient in routine surveillance at the National Influenza Center in Denmark. The detected influenza variant appeared distinct from any variant found previously in Denmark. Study: Severe Human Case of Zoonotic Infection with Swine-Origin Influenza A Virus,
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An article published in Critical Reviews in Food Science and Nutrition journal provides an overview of the role of gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Gut microbiome and anti-viral immunity in COVID-19. Image Credit: Design_Cells / Shutterstock Background SARS-CoV-2, the causative pathogen of the coronavirus disease
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The hypothalamus, one of the most complex brain regions in the mammalian nervous system, contains an astonishing heterogeneity of neurons that regulate endocrine, autonomic and behavioral functions. It not only regulates food consumption, water intake, body temperature, circadian rhythm and sleep to maintain the survival of individual organisms, but also controls puberty onset and reproductive
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The method by which a baby was delivered is associated with how its immune system will respond to two key childhood vaccines, research suggests. Babies born naturally were found to have higher antibody levels, compared with those born via Caesarian section after receiving their jabs that protect against bacteria that cause lung infections and meningitis.
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Asthma + Lung UK is calling for lung health to become an urgent priority after a damning report, released ahead of World COPD Day tomorrow, reveals that almost a quarter of people surveyed with the deadly lung disease chronic obstructive pulmonary disease (COPD), waited more than five years for a diagnosis, whilst one in eight waited
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A recent study posted to the medRxiv* preprint server examined adverse reactions after administration of a bivalent BNT162b2 coronavirus disease 2019 (COVID-19) vaccine booster. Vaccination is critical against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but emerging mutant variants of the virus impair the effectiveness of vaccines based on the original/wildtype SARS-CoV-2. Consequently, bivalent vaccines with
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Nov 11 2022 Since their first publication in 2010, the EULAR recommendations for the use of disease-modifying anti-rheumatic treatments (DMARDs) in people with RA have become a most important publication in the field, and their updates are relied upon by many healthcare professionals, professional organisations and other stakeholders to offer an up-to-date and robust analysis
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microRNAs can play a role in cancer development and are thought to exclusively suppress protein expression in dividing cells, such as tumor cells. But new research published in ACS Central Science shows that some of these tiny molecules can elevate the expression of a particular gene in dividing human cells and in cancer cells, challenging
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Exoskeletons — motorized mechanical devices attached to an individual’s body to assist movement — have been a popular feature in science fiction movies from Robocop to Iron Man as a means to give someone  superhuman skills. Ankle exoskeleton. Image Credit: Victoria University But researchers at Victoria University’s (VU) Institute for Health and Sport are using
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Launched today by the Medicines and Healthcare products Regulatory Agency (the MHRA), the seventh annual #MedSafetyWeek is running until 13 November to encourage widespread public engagement and improve patient safety by reporting suspected side effects associated with medicines and adverse incidents involving medical devices. This year’s campaign is a truly global effort and involves healthcare
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When life should have been ripe with possibilities, Mandy Murry instead faced a devastating diagnosis. Murry was diagnosed with cervical cancer when she was 22. She had her cervix and uterus removed to treat it. Her doctor believes the cancer was caused by the human papillomavirus (HPV). “I was expected to have that ‘happily ever
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In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders. Obesity results from higher energy intake compared to energy expenditure, which in turn results in an increase in adiposity. The calorie gap for preventing weight gain
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From PittconNov 3 2022Reviewed by Mychealla Rice Pittcon is a dynamic, transnational conference and exposition on laboratory science, a venue for presenting the latest advances in analytical research and scientific instrumentation, and a platform for continuing education and science-enhancing opportunity. Pittcon is for anyone who develops, buys, or sells laboratory equipment, performs physical or chemical
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Microplastics are not just tiny particles that can be ingested, they can also carry viruses, a University of Queensland study has revealed. The study, led by Associate Prof Jianhua Guo and Dr Ji Lu from UQ’s Australian Centre for Water and Environmental Biotechnology (ACWEB), investigated if microplastics have the ability to harbor viruses, including the
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