Children

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls. Published in Cell Reports, this is the first time that vascular endothelial cells could be reached for genome editing, since the usual way to deliver CRISPR/Cas9 – through a virus – does not
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In a large prospective study of just over 1,000 patients ages 17 and younger who were seen at the Baltimore Convention Center Field Hospital (BCCFH) testing site during a seven-month period last year, researchers from Johns Hopkins Medicine and collaborating institutions report that a rapid antigen test for SARS-CoV-2 — the virus that causes COVID-19
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Scientists have worked at an unprecedented speed to develop vaccines to fight against the ongoing coronavirus disease 2019 (COVID-19) pandemic. This pandemic has been caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus belonging to the family Coronaviridae. Study: Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. Image Credit: NIAID Background It
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A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours -; a feat that’s nearly unheard of in standard clinical care. “A few weeks is what most clinicians call ‘rapid’ when it comes to sequencing a patient’s genome
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is undergoing repeated and extensive mutational changes that have led to the emergence of several variants of concern (VOC) that often show higher transmissibility and immune-evasion characteristics. Among these VOCs include the Delta variant, which played a major role in the most recent wave of infections, hospitalizations,
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Researchers at Washington University School of Medicine in St. Louis have received three grants totaling more than $6.8 million to advance research on a novel imaging system to monitor uterine contractions. The electromyometrial imaging system, called EMMI, was invented and developed at Washington University. The device allows physicians to measure, in 3D, the electrical activity
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A new UCSF study that mapped the neural connections of newborns with two different kinds of brain injuries found the maps looked very different-;and were linked to significantly different developmental outcomes years later. The study, published today in PLOS ONE and led by UCSF pediatrics, neurology and radiology researchers, used diffusion MRI to visualize the
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At least 2% of the total global population have been infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) at some point during the current coronavirus disease 2019 (COVID-19) pandemic and more than 200 million infants were born since the onset of the pandemic. Millions of in-utero exposures to maternal SARS-CoV-2 infection are therefore likely.
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Thyroid hormone levels during pregnancy may predict preschool boys’ emotional and behavioral problems, according to a study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Thyroid hormones are crucial for normal development of a baby’s brain and nervous system. During the first trimester-;the first three months of pregnancy-;a baby depends on its
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A once-a-day antiretroviral medicine that is low-cost and easy for children to take is also more effective at suppressing HIV than standard treatments, according to a global trial led by researchers at UCL. The study, published today in The New England Journal of Medicine, found that dolutegravir-based regimens, which are already widely used to treat
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Researchers at Columbia University Mailman School of Public Health found marked decreases in orphanhood particularly double orphanhood, among adolescents in Rakai, Uganda, corresponding with the availability of antiretroviral therapy (ART) beginning in 2004 and of male medical circumcision in 2007. Until now, little had been known about the contribution of HIV combination prevention including ART
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The current coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has resulted in approximately 5.42 million deaths and over 286 million confirmed cases. The first instances of COVID-19 were reported in Wuhan, Hubei Province, China, in December 2019, with the majority of those affected having worked in a seafood and animal
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Children and staff who repeatedly test negative for COVID-19 after contact with someone who has the illness can safely remain in school if universal masking programs are in place, according to a new “test-to-stay” study report from the ABC Science Collaborative. The finding provides a safe alternative to quarantining people who have been exposed to
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As of December 28, 2021, over 282 million people have been infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide, of which over 5.4 million have died. In children, SARS-CoV-2 infection is usually asymptomatic or mild, which is in contrast to older individuals, who are associated with a greater risk of hospitalization and
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A new study suggests that a parenting educational intervention for first-born children is robust enough to influence the weight of second-born children, according to a paper published online in Obesity, The Obesity Society’s flagship journal. The findings presented make the Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) program the first educational intervention for
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A new study from Carnegie Mellon University and the University of Wisconsin-Madison has found children’s books may perpetuate gender stereotypes. Such information in early education books could play an integral role in solidifying gendered perceptions in young children. The results are available in the December issue of the journal Psychological Science. “Some of the stereotypes
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Researchers in Japan have evaluated hemodynamic factors that may help identify sites where aneurysms are likely to form. Detailed findings of this study are described in the article “Computational fluid dynamic analysis of the initiation of cerebral aneurysms” by Soichiro Fujimura et al., published today in the Journal of Neurosurgery. Unruptured aneurysms are most often
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A team led by scientists at Weill Cornell Medicine, Scripps Research and the University of Chicago has identified an important site of vulnerability on influenza viruses—a site that future influenza vaccines and antibody therapies should be able to target to prevent or treat infections by a broad set of influenza strains. The scientists, whose results
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HSE academics joined researchers from the Turner Scientific Research Institute for Children’s Orthopaedics to study how the brains of children with arthrogryposis control elbow flexion after muscle transplantation. They found that in such patients, more motor neuron activity occurs, which means that the start of a new movement requires more effort from the brain. The
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