Children

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs. The findings, published in Science Immunology, shed light on why antibiotics can weaken the effect of immunotherapies and could lead to
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In California, a Democrat and a Republican figured out how to pass the country’s toughest online privacy law protecting kids. If their experience is any indication, though, federal legislators can expect fierce pushback from Big Tech if they heed President Joe Biden’s call for similar action on a national scale. The law, modeled after legislation
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Rutgers research that may eventually enable far earlier autism diagnoses shows that typically developing infants perceive audio-video synchrony better than high-risk for autism infants. If follow-up research demonstrates that most infants who miss unmatched audio and video develop autism spectrum disorder (ASD), physicians may be able to diagnose the condition years earlier -; a potentially
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A study published in JAMA Network Open has found that in the US between 1999 and 2020, Black infants disproportionately died from necrotizing enterocolitis compared to White infants, despite overall improvements in the rates of death from the disease. Necrotizing enterocolitis (NEC) is one of the most common causes of death in preterm infants. Medically-fragile
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The results, published in eClinicalMedicine, have direct implications for clinical practice by providing a list of reference values for a multitude of cardiac parameters used in daily practice. Magnetic resonance imaging (MRI) has allowed scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) to produce an accurate picture of the healthy heart in adolescence. Using
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In a recent article published in JAMA Pediatrics, researchers conducted a population-based cohort study among 12 to 17-year-old adolescents in Ontario, Canada, to estimate the incidence of myocarditis or pericarditis after BNT162b2 vaccination. In addition, they determined whether these estimates varied with age, sex, and the interval between vaccine doses. Study: Myocarditis or Pericarditis Events
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Recent advances in newborn heart surgery have greatly reduced brain injuries in infants with congenital heart disease, according to a 20-year study by scientists at UCSF Benioff Children’s Hospitals and British Columbia Children’s Hospital (BCCH). The study, begun in 2001 and published this month in the Journal of the American College of Cardiology, analyzed brain
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New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) is the first study to show that childhood obesity is associated with an increased risk of four of the five recently proposed subtypes of adult-onset diabetes. The study is by Yuxia Wei, Institute of Environmental Medicine, Karolinska Institutet,
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Gestational diabetes and preeclampsia may be linked to slower biological development in infants, according to a new study led by USC. The research, published today in JAMA Network Open, found that newborns exposed to these two pregnancy complications were biologically younger than their chronologic gestational age. The infants’ biological or “epigenetic” age is based on
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Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in
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In a recent study published in the Morbidity and Mortality Weekly Report by the United States Centers for Disease Control and Prevention (CDC), researchers estimate the efficacy of the monovalent messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) in preventing symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the pediatric population between the
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Open spina bifida (SB), a neural tube defect (NTD), also known as myelomeningocele, remains the most complex congenital abnormality of the central nervous system compatible with long term survival. It gives rise to well known comorbidities and interventions, such as executive function challenges, urinary and bowel incontinence, and ventriculoperitoneal shunting. In this annual special issue
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For parents, the decision to vaccinate their kids against SARS-CoV-2 is complex, influenced by scientific evidence, political and social pressures, and views about individual versus collective benefits of vaccination, according to a new study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221401. Researchers conducted a qualitative study with in-depth interviews of 20 parents to understand
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By sifting through electronic health records of moms and babies using a machine-learning algorithm, scientists can predict how at-risk newborns will fare in their first two months of life. The new method allows physicians to classify, at or before birth, which infants are likely to develop complications of prematurity. A study describing the method, developed
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Pediatric patients with limited English proficiency (LEP) may face additional challenges when they present to an emergency room. However, researchers from Children’s Hospital of Philadelphia (CHOP) found that a multidisciplinary approach helped implement the services of interpreters earlier and significantly improved the identification of these patients to help them receive the care they need. The
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In a recent study published in the journal JAMA Network Open, researchers investigated whether the coronavirus disease 2019 (COVID-19) pandemic-related social changes such as attending classes from home and social distancing measures resulted in a sustained increase in children’s screen time. Study: Trends in Screen Time Use Among Children During the COVID-19 Pandemic, July 2019
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The American Academy of Pediatrics updated its guidance for evaluating and treating obesity last month, recommending proactive treatment for children and teens. But despite the fact that behavioral recommendations for obesity often recommend more physical activity and less screen time, there’s been little research on how combinations of physical activity and screen time can impact
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In a recent study posted to the medRxiv* preprint server, researchers used statistical modeling to estimate hospitalizations due to respiratory syncytial virus (RSV) infections in children under five years of age in 28 nations of the European Union (EU) and Norway.  Study: Defining the Burden of Disease of RSV in Europe: estimates of RSV-associated hospitalisations
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A single dose of the antibiotic azithromycin can help protect mothers from dangerous sepsis infections and death during vaginal childbirth, a sweeping new international study from a UVA Health scientist and his collaborators has found. Azithromycin, also known as Z-Pak, has already been shown to benefit women delivering by cesarean section. But the new findings
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Five teams led by Weill Cornell Medicine scientists have been awarded funding from the Starr Cancer Consortium in its 16th annual grant competition. The grants will fund research on the molecular origins and evolution of blood, bladder, breast, and colon cancers. The Starr Cancer Consortium was established in 2006 through the philanthropy of the Starr
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Researchers at the National Institutes of Health have discovered a new neurological condition characterized by issues with motor coordination and speech. They report their findings in npj Genomic Medicine. Scientists from NIH’s National Human Genome Research Institute (NHGRI) and Undiagnosed Diseases Program (UDP) identified three children with the condition, two siblings and an unrelated child.
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