Month: March 2021

Car T-cell therapy, described as a “living drug,” is now available for patients with relapsed/refractory multiple myeloma who have been treated with four or more prior lines of therapy. The US Food and Drug Administration (FDA) said these patients represent an “unmet medical need” when it granted approval for the new product ― idecabtagene vicleucel
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PRINCETON, N.J.–(BUSINESS WIRE) March 25, 2021 — Bristol Myers Squibb (NYSE: BMY) today announced primary results from the Phase 2/3 RELATIVITY-047 (CA224-047) trial evaluating the fixed-dose combination of relatlimab, an anti-LAG-3 antibody, and Opdivo (nivolumab) versus Opdivo alone in patients with previously untreated metastatic or unresectable melanoma. The trial met its primary endpoint of progression-free
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FDA Approves Abecma (idecabtagene vicleucel) as the First Anti-BCMA CAR T Cell Therapy for Relapsed or Refractory Multiple Myeloma PRINCETON, N.J., & CAMBRIDGE, Mass.–(BUSINESS WIRE) March 26, 2021 — Bristol Myers Squibb (NYSE: BMY) and bluebird bio, Inc. (Nasdaq: BLUE) today announced that the U.S. Food and Drug Administration (FDA) has approved Abecma (idecabtagene vicleucel;
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In this article AZN-GB The European Union could open up a “Pandora’s box” if it decides to restrict exports of coronavirus vaccines, a political analyst told CNBC last week. Vaccination drives in the 27-member bloc have been hindered by production issues. Anglo-Swedish firm AstraZeneca earlier this year cut its first-quarter target from 90 million doses
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Leigh syndrome is the most severe mitochondrial disease in children. It causes severe muscle weakness, movement defects, and intellectual disabilities. It usually leads to death within the first years of life. No causative treatment is currently available. One of the genes frequently mutated in patients is SURF1, which encodes for a protein involved in the
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The US Food and Drug Administration (FDA) has approved Medtronic’s Harmony Transcatheter Pulmonary Valve (TPV) System to treat severe pulmonary regurgitation in pediatric and adult patients who have a native or surgically repaired right ventricular outflow tract (RVOT). The Harmony TPV is the first nonsurgical heart valve to treat severe pulmonary valve regurgitation, which is
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Carbo Fix is an all natural formula to fight against belly fat, uncontrollable weight gain and intense hunger and cravings.   Carbo Fix is the only all-natural 6-ingredient blend in the world that help activate AMPk… …to target unexplained weight gain, excess belly fat and uncontrollable hunger. Now you can finally indulge in your favorite
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Todd Lencz, PhD A new genetic mutation in schizophrenia that blocks neuron communication in the brain may lead to novel treatment strategies and improve understanding of the mechanics of this disease. The discovery of this new gene, PCDHA3, could enhance the development of genetic-risk calculators “that may help us understand vulnerability to schizophrenia in high-risk individuals
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Emergency Medical Technician Lenny Fernandez, Medical Assistant Rodnay Moore and Physician Assistant-Certified Calvin Davis, left to right, prepare doses of the Pfizer COVID vaccine as the city of Vernon Health Department staff used the city’s new mobile health unit clinic to administer COVID-19 vaccinations to nearly 250 essential food processing workers at Rose & Shore,
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Type 1 diabetes is the most common metabolic disease in children and adolescents worldwide. It can be particularly dangerous as often there is no diagnosis until severe and sometimes life-threatening symptoms have already developed. The new ‘SINT1A‘ study explores the potential of a specific probiotic to strengthen the immune system early-on   in children with
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. People experiencing long-term symptoms following acute COVID-19 infection are increasingly meeting criteria for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a phenomenon that highlights the need for unified research and clinical approaches, speakers said at a press briefing Thursday held by the advocacy
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CarboFix is an all natural formula to fight against belly fat, uncontrollable weight gain and intense hunger and cravings.   CarboFix is the only all-natural 6-ingredient blend in the world that help activate AMPk… …to target unexplained weight gain, excess belly fat and uncontrollable hunger. Now you can finally indulge in your favorite carbs guilt-free… Knowing
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Overuse of alcohol among older adults is a mostly hidden story – for instance, National Drug and Alcohol Awareness Week (March 22-28 in 2021) is aimed at teens.  However, research suggests that one third of older drinkers develop the dependency later in life and that was before Covid-related stress and isolation.   How much drinking is
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You may have passed by the boards yourself, or seen them going viral online, but now we talk to the duo responsible for the inspirational messages left on London Underground customer information boards, to discover the story behind their iconic verses It was March 2017, and crowds of people were surging into North Greenwich tube
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. SARS-CoV-2’s infection sites are well known in the airways and other parts of the body, but new research indicates that the virus also infects mouth cells. The findings by Ni Huang, PhD, from the Wellcome Sanger Institute in Cambridge, United Kingdom,
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London, UK 18 March 2021 – GlaxoSmithKline plc (LSE/NYSE: GSK) today announced that the first patient has been dosed in the SWIFT-2 trial as part of the phase 3 clinical programme investigating the safety and efficacy of GSK3511294 (“GSK’294”) in severe eosinophilic asthma (SEA). GSK’294 is an investigational medicine with potential to be the first biologic
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Research has found that obesity and mental disorders such as depression and anxiety seem to often go hand in hand. Researchers at Baylor College of Medicine and collaborating institutions are providing new insights into this association by identifying and characterizing a novel neural circuit that mediates the reciprocal control of feeding and psychological states in
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March is National Nutrition Month! To honor National Nutrition Month, our resourceful dietician friends have created a number of blogs that will post during the month of March. These blogs will cover popular nutrition topics and myths. Check back often to see what new topics are being blogged about! Making sure that you get enough
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Members of the HMS community devote their careers to improving lives locally, nationally and globally through teaching, research, patient care and advocacy. Learn about some of their recent achievements and plans for the future. Like Harvard Medical School on Facebook: https://goo.gl/4dwXyZ Follow on Twitter: https://goo.gl/GbrmQM Follow on Instagram: https://goo.gl/s1w4up Follow on LinkedIn: https://goo.gl/04vRgY Website: https://hms.harvard.edu
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