Month: December 2021

In HER2-positive gastric cancer, the addition of pembrolizumab (Keytruda, Merck) to trastuzumab (Herceptin, Roche) and platinum-based chemotherapy led to a significant improvement in overall response rate, according to results from the first interim analysis of the KEYNOTE-811 phase 3, randomized clinical trial. The results of the trial, initially presented at the 2021 annual meeting of
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. With the Omicron variant of the coronavirus blazing across the United States, President Joe Biden offered reassurance on Tuesday to Americans who have followed public health guidance to get vaccinated and boosted, and delivered a stark warning to those who haven’t.
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In this article DAL Delta Air Lines airplanes at the Hartsfield-Jackson Atlanta International Airport (ATL) in Atlanta, Georgia, U.S., on Tuesday, Dec. 21, 2021. Elijah Nouvelage | Bloomberg | Getty Images Delta Air Lines CEO Ed Bastian on Tuesday asked the Centers for Disease Control and Prevention to halve its recommended quarantine time for people
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Pairing a novel cytotoxic agent with bevacizumab (Avastin) failed to improve progression-free survival (PFS) versus standard therapy in older patients with metastatic colorectal cancer (mCRC) ineligible for intensive therapy, a randomized trial showed. Investigator-assessed PFS was 9.4 months with trifluridine/tipiracil (Lonsurf) plus bevacizumab and 9.3 months with capecitabine plus the angiogenesis inhibitor. PFS by blinded
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Children and adolescents who show persistent high levels of anxiety are more likely to become psychotic in their early 20s, according to a new study. But treating early anxiety by targeting stress hormones and non-resolving inflammation during childhood and teenage years could help to reduce the risk of young adults going on to develop psychosis.
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In a recent preprint study posted to the medRxiv* preprint server, researchers conducted a systematic review and meta-analysis to determine the impact and risk of severe acute respiratory syndrome-associated coronavirus 2 (SARS-CoV-2) in cancer patients based on age, tumor type, and therapy. Study: A comprehensive systematic review and meta-analysis of the global data involving 61,532
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There’s a sort-of unspoken, but widely acknowledged, ‘life path’ we’re all expected to follow – but none of our journeys are exactly the same. Here, we’re exploring the mental health impact of deviating from the predicted ‘life milestones’ course, and how to handle it The word ‘milestone’ is said to date back to the third
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. In a scientific statement issued today, the American Heart Association (AHA) says it fully supports updated federal guidance regarding COVID-19 vaccines and boosters and implores all eligible Americans to get vaccinated as soon as possible. Late last week, the US Centers
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I think we thought we saw this coming. And I think we tried to warn everybody. Approaching 2 years into the pandemic, with hundreds of thousands of lives lost and millions sickened, it feels like we’re no closer to an effective public health system prepared to handle what comes next, instead of reacting to things
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A team of scientists at the University of Oslo, Oslo University Hospital (OUH) Radiumhospitalet and Karolinska Institutet, led by Professor Johanna Olweus, has developed a new type of immunotherapy for cancer. The new treatment makes the patient’s immune cells “believe” that cancer is a transplanted organ that should be rejected. The immune cells then attack
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The FDA approved the only biologic for severe asthma without any phenotype or biomarker limitations, manufacturers AstraZeneca and Amgen announced Friday. The first-in-class biologic tezepelumab-ekko (Tezspire) is indicated as an add-on maintenance treatment for patients ages 12 and older with severe asthma. It is not intended for acute bronchospasm or status asthmaticus. As a first-in-class
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New research suggests that prenatal coronavirus disease 2019 (COVID-19) exposure increases the risk for neurodevelopmental disorders in the baby’s first year of life. The risk of neurodevelopmental disorders increased if COVID-19 infection occurred in the third trimester. The majority of diagnosed neurodevelopmental disorders involved motor and language problems. Because children born to previously infected mothers
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Breakthrough infections could lead to an eventual end game of the COVID-19 pandemic: This is what scientists are saying after conducting tests on live SARS-CoV-2 virus exposed to blood samples collected from vaccinated individuals.  Study On COVID-19 Protection In a study published in the Journal of the American Medical Association, researchers from the Oregon Health
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A year ago, our incredible columnist Grace Victory began her maternity leave – but no one could ever have predicted the chain of events that would unfold. With raw honesty, Grace shares the traumatic journey she’s been through, after catching Covid-19 late in her pregnancy, and being put in an induced coma. Now, she’s back,
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Dec. 17, 2021 — Pfizer’s COVID-19 vaccine for children ages 2 to 5 years old fizzled in clinical trials, the company said on Friday, signaling a further delay in getting a vaccine to preschoolers just as Omicron bears down on the U.S. In
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U.S. President Joe Biden speaks in the Eisenhower Executive Office Building in Washington, D.C., U.S., on Wednesday, Nov. 3, 2021. Al Drago | Bloomberg | Getty Images A federal appeals court has reinstated the Biden administration’s vaccine and testing requirement for private businesses that covers about 80 million American workers. The ruling by the 6th
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Today, CDC released two reports in the Morbidity and Mortality Weekly Report highlighting the use of test-to-stay practices used in schools to minimize absenteeism and learning loss which can occur during traditional quarantine at home. In light of this updated data, CDC has added information on test-to-stay practices to our K-12 Transmission Science Brief and
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