Month: December 2021

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein is a trimeric transmembrane protein formed of two subunits that must be cleaved by a host protein to function. The S1 subunit contains a receptor-binding domain (RBD) that binds to angiotensin-converting enzyme 2 (ACE2) to permit viral cell entry. Many variants show mutations in this
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How to put on a festive bird buffet this winter There’s nothing quite like winter for comfort food: Sunday roasts, warm apple pie, a mug of hot chocolate by the fire. And that’s just for the humans – did you know, you can help spread the festive gastronomic joy with your local birds, too? Any
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The intention to vaccinate children against COVID-19 was lower among vaccine-hesitant parents when compared with parents who were willing to or had already received the COVID vaccine, a new survey finds. “Parental vaccine hesitancy is a major issue for schools resuming
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A man wears an anti-vaccine button as people and teachers protest against New York City mandated vaccines against the coronavirus disease (COVID-19) in front of the United States Court in Manhattan in New York City, New York, U.S., October 12, 2021. Mike Segar | Reuters A U.S. district court in Georgia halted the Biden administration’s
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Use of high-flow oxygen was associated with less of a need for mechanical ventilation and a shorter time to recovery compared with conventional oxygen therapy in patients with severe COVID-19, a randomized trial in Colombia found. Thirty-four percent of patients randomized to high-flow oxygen through a nasal cannula were intubated by day 28 compared with
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Interventions to de-escalate use of inhaled corticosteroids (ICS) in patients with chronic obstructive pulmonary disease (COPD) are necessary and beneficial, researchers said during the federal posters session at the American Society of Health-System Pharmacists (ASHP) Midyear virtual meeting. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines recommend long-acting beta2-agonists (LABA) and long-acting muscarinic
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein binds the host cell surface receptor angiotensin-converting enzyme 2 (ACE2). It is a glycosylated protein and is a target for vaccines and therapeutics against the virus. Unraveling the structure of the membrane-bound spike protein will further our understanding of the virulence and pathogenicity of the
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For a decade, Hayley suffered crippling symptoms without knowing what was wrong. Diagnosed at last, she is now able to control the condition that was ruining her life, and uses her knowledge and expertise to help others The first symptoms of endometriosis – a condition where tissue similar to the lining of the womb starts
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Patients with focal nonmotor seizures experience a “disproportionate delay to diagnosis” compared with those with focal motor seizures, especially among teens, new research suggests. Retrospective analyses from an international, multisite study showed that although both adults and children experienced delays in receiving a diagnosis of focal epilepsy, these delays were significantly longer among younger patients.
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Increased inflammation via cytokine storms has led to multiple heart complications in coronavirus disease 2019 (COVID-19) infections. But in order to treat these cardiovascular problems, doctors will need a better understanding of the relationship between cytokine storms and cardiovascular proteins. New research suggests that Th1, Th2, and Th17 inflammatory pathways are involved in the overproduction
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Pull up a blanket, head to your nearest window, and enjoy the peace gluggavedur can bring How’s the weather looking where you are? If, like me, you’re in the depths of winter in the UK, chances are it’s grey, chilly, and perhaps a little rainy. This kind of weather has been affectionately named ‘gluggavedur’ in
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