Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases. However, the mechanisms involved in engraftment-;when the cells start to grow and make healthy blood cells after being transplanted into a patient-;are poorly understood. A recent study led
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Paxlovid, a Pfizer’s coronavirus disease (COVID-19) pill, is seen manufactured in Ascoli, Italy, in this undated handout photo obtained by Reuters on November 16, 2021. Pfizer | Handout | via Reuters President Joe Biden on Tuesday said the Americans who test positive for Covid-19 can receive antiviral pills for free at local pharmacies and community
I started planning my escape in late 2020. I would find a way to quit healthcare, to cease being a practicing physician altogether. Living the life of a doctor-mom, I felt consumed with daily obligations and duties. Guilt plagued me for feeling burdened by this life, for feeling it was a monotonous prison. The guilt
Seasons change… Trees and flowers start budding to form colorful landscapes. Green-leafed trees change into a rainbow of fall colors. Those fall colors turn into a winter wonderland. Sounds pretty, right? What isn’t pretty — the misery that seasonal allergies often bring. Even though allergies cause problems year round, a number of environmental allergens “peak”
PHOENIX — In some patients with eosinophilic asthma, dupilumab (Dupixent) offered the highest chance of better lung function, although the agent also carried the highest odds of serious adverse events (AEs), a researcher reported. In an indirect treatment comparison of dupilumab, mepolizumab (Nucala), and benralizumab (Fasenra), patients with eosinophil counts ≥300 cells/μL treated with dupilumab
Researchers from the Mitochondrial Medicine Frontier Program at Children’s Hospital of Philadelphia (CHOP) have found that developmental delays associated with Leigh syndrome, the most common pediatric mitochondrial disorder, may occur earlier than previously recognized – even before metabolic stroke and regression – which could provide clinicians with an opportunity for earlier diagnosis and therapeutic interventions.
Strong new evidence on the need to use an appropriately sized cuff in blood pressure (BP) measurement has come from the cross-sectional randomized trial Cuff(SZ). The study found that in people in whom a small adult cuff was appropriate, systolic BP readings were on average 3.6 mm Hg lower when a regular adult size cuff
A landmark UN report warned Monday that time had nearly run out to ensure a “liveable future” for all, detailing a horrifying “atlas of human suffering” and warning that far worse was to come. Species extinction, ecosystem collapse, insect-borne disease, deadly heatwaves and megastorms, water shortages, reduced crop yields — all are measurably worse due
With endometriosis awareness week taking place at the start of March, Jenna Farmer shines a spotlight on the painful gynaecological condition that affects one in 10 women, yet can take up to seven and a half years to diagnose. Endometriosis is thought to affect 10% of women of reproductive age across the world, but there’s
Dr Dana Telem About one in six patients undergoing hernia repair require reoperation within 10 years, according to a new research letter published March 1 in JAMA. Patients who underwent minimally invasive hernia repair had a higher incidence of reoperation than those who underwent open repairs. In the United States, surgeons perform more than 1
According to Spokane Regional Health District Health Officer Francisco Velazquez, omicron’s subvariant, also known as BA.2, allegedly causes distinct symptoms compared to previous strains. When speaking with CBS-affiliated news station KREM 2 News, Velazquez said that BA.2 is more contagious than the original and causes different symptoms, such as dizziness. Although case numbers are falling,
New research from the University of East Anglia (UEA) and Quadram Institute reveals how our immune system can be triggered to attack cancer cells. The research, published today in the Journal of Clinical Investigation, could help develop new approaches to treating people with leukemia. The team studied acute myeloid leukemia – a blood cancer which
Nora Gossett, 7, reacts as she receives the Pfizer-BioNTech COVID-19 vaccine from Sophia Jan, MD, while her father Jeff Gossett, MD, holds her hand at Cohen Children’s Medical Center as vaccines were approved for children aged 5-11, amid the coronavirus disease pandemic, in New Hyde Park, New York, November 4, 2021. Andrew Kelly | Reuters
The COVID-19 pandemic has brought to the forefront inequities and vulnerabilities that have always existed in our healthcare system. Yet, as the pandemic persists, policies that further limit access to care for underserved populations continue to be pushed forward. For about a year now, providers have been ringing alarm bells about devastating cuts to Medicare
PHOENIX — Biologic medications sent severe asthma into remission in a substantial proportion of patients, according to a study presented here at the annual meeting of the American Academy of Allergy, Asthma & Immunology. About 35% of 908 patients who took biologic treatments for at least 12 months were able to achieve remission status, reported
Antibiotics provide no benefit in preventing future recurrent wheezing in babies hospitalized with respiratory syncytial virus (RSV), according to a new study led by Washington University School of Medicine in St. Louis. And there is some evidence that antibiotics may make wheezing worse. The antibiotic azithromycin has anti-inflammatory properties that can be beneficial in some
It’s often easy to write off procrastination as laziness or complacency, but what’s really going on under the surface? To do the things you should do can be the hardest thing in the world – or the easiest. Isn’t it funny how sometimes we can just get on and do the things that matter, and
The platelet content of a clot may be at least as strong a predictor of outcome and mortality following mechanical thrombectomy as fibrin content, new data suggest. Researchers analyzed clot composition for about 1000 patients with acute ischemic stroke who were included in a prospective, multicenter registry. Among clots rich in red blood cells (RBCs),
People should be wary of two new COVID-19 symptoms observed in patients down with the new omicron subvariant, BA.2. Stealth Omicron Symptoms A month after the omicron subvariant BA.2 made the headlines for being a “stealth” version of the novel coronavirus, health officials are now warning of two new symptoms not typically seen in patients
This year’s Eating Disorders Awareness Week campaign calls for more robust training for GPs. Here we chat to Beat to learn more Eating disorders are complex mental health conditions. On the surface they may seem to be about food and weight, but dig deeper and you’ll see there’s a lot more going on. As someone
SACRAMENTO — Single-payer health care didn’t stand a chance in California this year. Even in this deep-blue bastion, Democratic lawmakers shied away from legislation that would have put state government in charge of health care and taxed Californians heavily to do so — a massive transformation that would have forced them to take on the
Capacity limits on social gatherings and other similar restrictions arguably made sense in the early days of the pandemic. We knew little then about the coronavirus, had virtually no way to treat it, and needed to protect the most vulnerable. But those restrictions came at the expense of millions of Americans’ mental health. And their
Becoming a Doctor is one of the most noble and amazing professions one can choose. Here are the reasons why being a doctor is awesome! And why the arduous journey of a pre-med and medical student is worth it! Learn more about our courses (**ON SALE for a limited time with a 30 day MONEY-BACK
People who are more physically fit are less likely to develop Alzheimer’s disease than people who are less physically fit, according to a preliminary study released today, February 27, 2022, that will be presented at the American Academy of Neurology’s 74th Annual Meeting being held in person in Seattle, April 2 to 7, 2022 and
Travel restrictions are quickly disappearing in Europe, with new announcements coming by the week — and, more recently, by the day. Changes to eliminate Covid-related travel rules gained momentum in January, as a wave of omicron-related infections engulfed the continent. But parts of Europe didn’t wait to act. Citing high vaccination rates and the
Deep learning identified subgroups of patients with primary progressive multiple sclerosis (PPMS) who may respond to disease-modifying therapy, researchers said. A trained model separated responders and non-responders across a range of predicted effect sizes, reported Jean-Pierre Falet, MD, of McGill University in Montreal, Canada, at the ACTRIMS Forum 2022, the annual meeting of the Americas
PHOENIX — Nearly three-fifths of patients with eosinophilic esophagitis (EoE) achieved remission after treatment with dupilumab (Dupixent), researchers reported. In a 6-month study, 58.8% of adults and adolescents treated with dupilumab achieved histological remission compared to 6.3% in the placebo group (P<0.0001), according to Marc Rothenberg, MD, PhD, of Cincinnati Children’s Hospital, in a pre-recorded