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As winter begins and the holidays are in full swing, the COVID-19 pandemic has entered another worrying phase. Emergence of the omicron variant, along with increasing rates of infections, have left many people unsure about their holiday plans. On Dec. 2, 2021, President Joe Biden outlined a series of actions to respond to the COVID-19
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Fibrosis-4 index (FIB-4) scores are strongly associated with severe liver disease outcomes in a primary care population, both in patients with known chronic liver disease and those without known CLD. The result could help identify patients with CLD before their condition becomes severe. FIB-4 has previously shown utility in predicting the risk of advanced fibrosis
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Please be advised that this video contains graphic footage of surgery. This video demonstrates a total thyroidectomy and central (level VI) neck dissection performed and narrated by Dr. Daniel L. Price. Series Editors: Katherine P. Wallerius, M.D.; Andrew J. Goates, M.D.; Matthew L. Carlson, M.D. To learn more about the Department of Otorhinolaryngology at Mayo
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End-of-life discussions happen too late in the treatment of high-risk acute myelogenous leukemia, according to a review of 200 patients at Massachusetts General Hospital and the Dana Farber Cancer Institute, Boston. The prognosis isn’t good for high-risk AML, defined in the study as either relapsing/recurrent disease or a diagnosis made past the age of 59 years. Almost
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SAN ANTONIO — A headline-making antibody-drug conjugate (ADC) continued to impress breast cancer specialists by demonstrating activity in tumors with low HER2 expression and in some breast cancers with undetectable HER2. As expected, trastuzumab deruxtecan (T-DXd, Enhertu) showed robust activity in HER2-overexpressing metastatic breast cancer, producing objective responses in 71% of patients. Additionally, 38% of
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An immunotherapy harnessing the immune system’s “natural killer” cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return. Now, researchers at Washington University School of Medicine in St. Louis have shown, in a small clinical trial, that the same natural killer cells also can help some children and young
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A novel artificial intelligence score provides a more accurate forecast of the likelihood of patients with suspected or known coronary artery disease dying within 10 years than established scores used by health professionals worldwide. The research is presented today at EuroEcho 2021, a scientific congress of the European Society of Cardiology (ESC). Unlike traditional methods
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Patients ages 65 years and older with atopic dermatitis (AD) have similar disease severity when compared with younger adult patients, but they have more profound sleep disturbances, especially trouble staying asleep. Those are key findings from a cross-sectional study that Jaya Manjunath, BS, and Jonathan I. Silverberg, MD, PhD, MPH, presented during a poster session
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Please be advised that this video contains graphic footage of surgery. This video demonstrates a lingual frenulectomy (tongue tie release) in an adolescent boy for speech difficulty performed by Drs. Balakrishnan and Barnes. Chapter Authors: Jason H. Barnes, M.D., Karthik Balakrishnan, M.D., M.P.H. Series Editors: Andrew J. Goates, M.D., Matthew L. Carlson, M.D. To learn
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ATLANTA — An experimental bi-specific, T-cell engaging (BiTE) monoclonal antibody, mosunetuzumab (Genentech), has induced high response rates and long-duration responses as monotherapy for patients with heavily pretreated, relapsed or refractory follicular lymphoma in a phase 2 expansion study. At a median follow-up of 18.3 months, 54 of 90 patients (60%) had a complete response, and
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The 24-hour news cycle is just as important to medicine as it is to politics, finance, or sports. At MedPage Today, new information is posted daily, but keeping up can be a challenge. As an aid for our readers, here is a 10-question quiz based on the news of the week. Topics include COVID vaccine
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For many emerging adults, the period between 18 and 25 years of age marks a stage of life to explore what matters to them and assume new legal rights and responsibilities, including their own private health information and medical decision-making. But this transition to independence can create sticky family dynamics, especially when emerging adults remain
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En las primeras etapas de la pandemia, le pedimos a la experta en gratitud, Antonia Albany, que compartiera algunos pensamientos sobre cómo permanecer agradecido en circunstancias difíciles. Estamos repasando sus pensamientos, que son tan relevantes este año como lo fueron el año pasado. Durante nueve largos meses de COVID, hemos hecho todo lo posible para
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Okinawa Institute of Science and Technology Graduate University (OIST) and Ryukyu Football Club Co., Ltd. (FC Ryukyu) have today launched a new partnership, aimed at understanding how athletes’ minds behave during team sports. The insights into brain science gained during the project may one day con-tribute to improving the performance of professional athletes in team
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While it’s often a time of overindulgence, here we’re sharing some essential ideas on how to reduce waste this winter It’s a season for giving, but showing someone you care doesn’t have to cost the Earth. How often do you realise you’ve gotten carried away, and stocked the cupboards with enough festive snacks to last
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CUTHBERT, Ga. — Lacandie Gipson struggled to breathe. The 33-year-old woman with multiple health conditions was in respiratory distress and awaiting an ambulance. About 20 minutes after the emergency call, it arrived. Southwest Georgia Regional Medical Center in Cuthbert, Georgia The Cuthbert home where Gipson lived was less than a mile from Southwest Georgia Regional
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Yoga added to conventional therapy for vasovagal syncope (VVS), when patients faint after a sudden drop in heart rate and blood pressure, can reduce symptoms and improve quality of life, new research suggests.  A small, open-label trial conducted in New Delhi, India, showed that participants practicing yoga reported an improvement in VVS symptoms after only
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A healthcare worker administers a Covid-19 swab test at a testing site at Tropical Park in Miami, Florida, U.S., on Friday, Aug. 6, 2021. Eva Marie Uzcategui | Bloomberg | Getty Images Several southern U.S. states, including Texas, Georgia, Louisiana and Florida, have confirmed cases of the omicron Covid-19 variant as the highly mutated strain takes
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Sun exposure was linked to a lower risk of pediatric-onset multiple sclerosis (MS), a case-control study showed. Spending 30 minutes to 1 hour outdoors daily during the most recent summer was associated with 52% lower odds of developing pediatric MS compared with spending less than 30 minutes outside per day (adjusted OR 0.48, 95% CI
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Adapted with permission from the American Heart Association. Most young people under the age of 21 who developed suspected COVID-19 vaccine-related heart muscle inflammation known as myocarditis had mild symptoms that improved quickly, according to new research published today in the American Heart Association’s flagship journal Circulation. Myocarditis is a rare but serious condition that
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“When we get too caught up in the busyness of the world, we lose connection with one another – and ourselves.”– Jack Kornfield December offers great opportunities for learning about how our intercultural world celebrates.  Among celebrations during this month are: Hanukkah (Jewish) Christmas Day (Christian) Boxing Day (Australian, Canadian, English, Irish) Kwanzaa (African American)
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Coronaviruses pose a major threat to the global healthcare systems and include zoonotic pathogens such as severe acute respiratory syndrome (SARS-1), severe acute respiratory syndrome coronavirus 2 (SARS-2) and Middle East respiratory syndrome coronavirus (MERS). Coronaviruses enter the host cells using the viral spike (S) protein with the fusion peptide (FP) of the S protein
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