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Treatment for Wilson’s Disease FDA Acceptance for Filing of New Drug Application (NDA) for Trientine Tetrahydrochloride (TETA 4HCl) for the treatment of Wilson’s Disease NDA supported by positive data from Phase 3 CHELATE clinical trial TETA 4-HCl previously granted Orphan Drug Designation for first-line treatment of Wilson’s Disease Paris, France – 02 September 2021 – Orphalan
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Acclaimed actor, director and now author David Harewood, joins Happiful’s podcast to talk about his new book Maybe I Don’t Belong Here: A Memoir of Race, Identity, Breakdown and Recovery David Harewood describes himself as an actor, director, writer and “more importantly, a resilient survivor of psychosis, trying to reduce the stigma attached to mental
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. It was supposed to be a turning point in the coronavirus pandemic for Erin Tokley, a longtime Philadelphia police officer, Baptist minister and 47-year-old father of three. It was supposed to be the day of his vaccine appointment. Instead it was
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WOODSIDE, CALIF. — On the same day that former Theranos CEO Elizabeth Holmes was granted a delay in her criminal fraud trial due to a pregnancy, her partner was issued a traffic citation. William “Billy” Evans received a citation on March 17 for “failure to display license place,” according to San Mateo County court records.
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LA ROCHELLE, France. Sept 6, 2021 – Valbiotis, a French research and development company committed to scientific innovation for preventing and combating metabolic diseases, announces that it has completed the recruitment of 120 volunteers for the Phase II HEART clinical study at the beginning of September 2021, in accordance with the schedule announced by the
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One study of an immunotherapy for reducing chronic obstructive pulmonary disease (COPD) exacerbations missed its primary endpoint and failed to show a statistically significant benefit even in the subgroup that showed the greatest response. Another study, involving a similar product, showed results so dramatic that an independent expert suspected they were “too good to be
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In the early days of the pandemic, scientists have already established that the younger population is not really affected by COVID-19 because of the difference in their immune system compared to adults. However, children are still at risk since they can get infected with the novel coronavirus. This urged government leaders and medical experts to
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A novel liquid biopsy test has been shown to distinguish between patients with neurofibromatosis type 1 (NF1) who have benign plexiform neurofibroma (PN) precursor lesions from patients who have malignant peripheral nerve sheath tumors (MPNST), say authors of a multi-institutional cross-sectional study. “Transformation from PN to MPNST is challenging to detect by imaging…or by biopsy…which
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Simon Collins, businessman, philanthropist and former chair of KPMG UK, has been making connections in the City for almost four decades. Now, as chair of our philanthropic giving circle the Catalyst Club, which turns 10 this year, he’s making connections of a different kind. Here, he tells us why he’s so passionate about uniting people
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Have you ever found yourself confused by guidance from a newspaper? Listened to a politician continuously deny a fact when science says otherwise? Read a news story with scary health facts that don’t add up elsewhere? This type of reporting actually has a name: media gaslighting. Gaslighting is a form of psychological manipulation that seeks
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A “quadpill” containing quarter doses of four blood pressure (BP)-lowering medications was more effective than monotherapy for initial treatment of hypertension, with similar tolerability, in the 1-year, phase 3 QUARTET randomized, active-control trial. Clara Chow, MD, PhD, academic director of the Westmead Applied Research Centre, University of Sydney, Australia, presented the findings in a late-breaking trial
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Volunteers are trained by St John Ambulance instructors in the correct use of PPE during their course to administer Covid-19 vaccines at Manchester United Football Club on January 30, 2021 in Manchester, England. Christopher Furlong | Getty Images News | Getty Images When coronavirus vaccines were developed, trialed and authorized for emergency use in record
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Since it was first detected in December 2019 in Wuhan, China, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the virus that causes coronavirus disease 2019 (COVID-19) – has infected over 217 million people worldwide. To date, this has led to over 4.56 million deaths worldwide. The COVID-19 pandemic continues to affect more
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Scientists from Israel have recently explored the effectiveness of two-dose and three-dose regimens of the BNT162b2 coronavirus disease 2019 (COVID-19) vaccine (Pfizer/BioNTech) to reduce viral load in breakthrough infections caused by the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Furthermore, they observe that the gradual reduction of vaccine efficacy against viral load
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Exercise capacity in patients with chronic obstructive pulmonary disease (COPD) increased substantially following a single IV iron infusion, a researcher reported. With patients’ tolerance for physical activity measured with two standard assessments — the 6-minute walk test (6MWT) and a constant work-rate exercise test — more than half the patients receiving the infusion achieved the
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The cerebral venous thrombosis (CVT) that occurs as part of the rare adverse reaction to the adenovirus vector COVID-19 vaccines from Astra Zeneca and Johnson & Johnson is much more severe and associated with greater mortality and disability than sporadic CVT,
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Ride the waves and tap into self-care with these tips Have you ever had an emotion that felt ‘too much’, or feared that your feelings would overwhelm you? While emotions have an adaptive purpose – to help us stay safe, make decisions, communicate, and build social bonds – there are times when they become so
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Serious health risks were no more common in the first 3 weeks after Pfizer/BioNTech or Moderna COVID-19 vaccination compared with 22-42 days later, a first-of-its-kind study of more than 6 million people reveals. mRNA vaccination was not associated with greater risks
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American Airlines flight 718, the first U.S. Boeing 737 MAX commercial flight since regulators lifted a 20-month grounding in November, takes off from Miami, Florida, December 29, 2020. Marco Bello | Reuters American Airlines and Alaska Airlines will no longer cover Covid-19 quarantine time for employees who aren’t vaccinated against the virus, the latest push
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SAN FRANCISCO, Sept. 3, 2021.  Quantum Leap Healthcare Collaborative, the sponsor of the I-SPY COVID Trial, today announced that the Famotidine Celecoxib arm has been dropped from the trial due to futility, based on the low likelihood of success. The Famotidine Celecoxib combination was chosen for testing because of their anti-histamine and anti-inflammatory mechanism of
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Licensing productive transcription through RNA polymerase II stabilityPlay Video Credit: Northwestern University Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell. According to the study, the presence of a protein called SPT5 serves as a “passport,” determining
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