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The study focused on multisystem inflammatory syndrome in children (MIS-C), an inflammatory response involving multiple organs that can occur weeks after infection with SARS-CoV-2, the virus that causes COVID-19. Although most patients improve with medical care, more than half the MIS-C cases in the U.S. require ICU admission, and the condition can be deadly. A
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Most highly allergic adults were able to safely receive the two-dose series of the Pfizer/BioNTech COVID-19 vaccine (BNT162b2; Comirnaty), a prospective single-center study found. Of 429 highly allergic patients who received the first dose of the mRNA vaccine, mild allergic reactions occurred in 1.4% and 0.7% experienced anaphylaxis, reported Nancy Agmon-Levin, MD, of Sheba Medical
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Learn how to let go of self-deprecation, and instead talk positively about your achievements Most of us have been there: you are introduced to someone new as, “A talented writer/accountant/marketer/musician” etc. Rather than accept the compliment, chances are you swiftly downplay your strengths, and feel a little embarrassed. But why are we so quick to
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The anti-inflammatory agents colchicine and icosapent ethyl (Vascepa; Amarin) failed to provide substantial benefits in separate randomized COVID-19 trials. Both were reported at the European Society of Cardiology (ESC) Congress 2021. The open-label ECLA PHRI COLCOVID trial randomized 1277 hospitalized adults (mean age 62 years) to usual care alone or with colchicine at a loading
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Proper stretches before and after a run can improve your performance and decrease your risk of injury. Dusty Marie Narducci, M.D., Sports Medicine Fellow, discusses the importance of stretching and offers demonstrations of several dynamic and static stretches.
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Treatment for Prevention of COVID-19 Pfizer and BioNTech Initiate Rolling Submission of Supplemental Biologics License Application to U.S. FDA for Booster Dose of Comirnaty in Individuals 16 and Older New Phase 3 data show booster (third) dose of Comirnaty induces significant SARS-CoV-2 neutralizing antibody titers and demonstrated a favorable safety and tolerability profile SARS-CoV-2 neutralizing
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ATLANTA, Aug. 30, 2021 /PRNewswire/ — UCB announced today that the U.S. Food and Drug Administration (FDA) has approved an expanded indication for Briviact (brivaracetam) CV tablets, oral solution, and injection to treat partial-onset seizures in patients as young as one month of age.2 This is the first time that the IV formulation of Briviact
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What is it that makes a simple jigsaw puzzle such an effective mindfulness practice? It’s the rainy day classic that became a lockdown essential, and while there’s nothing new about puzzles (the first jigsaw is thought to have been created in 1762), many of us are just starting to realise the potentially mindful boost that
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Patients on immunosuppressive or immunomodulatory therapy should receive a third dose of either the Pfizer-BioNTech COVID-19 vaccine or the Moderna COVID-19 vaccine at least 28 days after the second dose of either of these two mRNA vaccines, according to updated recommendations
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Taiwan is banking on a homegrown Covid-19 shot to speed up its inoculation program as the island and many countries struggle to secure vaccine deliveries from major drug companies. The locally produced Covid vaccine from Medigen Vaccine Biologics was rolled out last week, with President Tsai Ing-wen receiving her first shot of the two-dose vaccine
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Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived. Undaunted, stem cell scientists, cell biologists, infectious
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A new study from the Prevention Research Center of the Pacific Institute for Research and Evaluation finds that recreational marijuana legalization may increase the risk of alcohol and marijuana co-use among adolescents. The study examined the association between recreational marijuana legalization in California in November 2016 and alcohol and marijuana co-use among underage youth. The
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Public health authorities have been persuading the general masses to get the COVID-19 booster shots once they have become available. But the guidance has mostly been for those who received the mRNA vaccines from Pfizer and Moderna, leaving recipients of Johnson & Johnson’s Janssen vaccine wondering if they also need the additional dose of the vaccine. 
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As we get older, it’s more and more likely that more of us will live alone.  According to the latest information from the Merck Manuals, some 28% (14.7 million) of US community-dwelling older adults live alone (21% of older men and 34% of older women). The numbers increase with age – some 44 percent of
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elamipretide Treatment for Barth Syndrome Stealth BioTherapeutics Submits Elamipretide New Drug Application to FDA for Treatment of Barth Syndrome BOSTON, Aug. 24, 2021 /PRNewswire/ – Stealth BioTherapeutics Corp (Nasdaq: MITO), a clinical-stage biotechnology company focused on the discovery, development, and commercialization of novel therapies for diseases involving mitochondrial dysfunction, today announced the submission of a New Drug Application (NDA)
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PRINCETON, N.J.–(BUSINESS WIRE) August 20, 2021 — Bristol Myers Squibb (NYSE: BMY) today announced that Opdivo (nivolumab) 240 mg every two weeks or 480 mg every four weeks (injection for intravenous use) was approved by the U.S. Food and Drug Administration (FDA) for the adjuvant treatment of patients with urothelial carcinoma (UC) who are at
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A new noninvasive procedure is safe and effective for treating patients with mild Alzheimer’s disease (AD), new research suggests. The approach uses MRI-guided low-intensity focused ultrasound (FUS) and injected microbubbles to temporarily open the blood-brain barrier (BBB). In a small group of patients, the procedure was significantly associated with reduced amyloid plaque and cognitive decline.
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An Israeli man receives a third shot of coronavirus disease (COVID-19) vaccine as country launches booster shots for over 30-year-olds, in Rishon Lezion, Israel August 24, 2021. Nir Elias | Reuters Israeli lawmakers are keen to avoid another lockdown after overseeing one of the world’s fastest vaccination drives. New daily coronavirus infections, however, have just
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Finerenone (Kerendia) prevents cardiovascular (CV) and some renal events in type 2 diabetes patients with earlier stages of kidney disease, the FIGARO-DKD trial showed. In the trial’s stage 1 to 4 kidney disease patients with moderate-to-severe albuminuria, the nonsteroidal mineralocorticoid receptor antagonist (MRA) reduced the composite of CV death, nonfatal myocardial infarction or stroke, or
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ABBOTT PARK, Ill., Aug. 27, 2021.  Abbott today announced results of the landmark GUIDE-HF clinical trial, a 1,000 patient randomized study designed to assess the benefits of the CardioMEMS HF System in people living with NYHA Class II, III and IV heart failure. Data adjusted for the impact of COVID-19 show a strong reduction in
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Children with infantile spasms, a rare form of epileptic seizures, should be treated with one of three recommended therapies and the use of non-standard therapies should be strongly discouraged, according to a study of their effectiveness by a Weill Cornell Medicine and NewYork-Presbyterian investigator and collaborating colleagues in the Pediatric Epilepsy Research Consortium. Early treatment
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In patients with coronary artery disease scheduled for a percutaneous intervention (PCI), fractional flow reserve (FFR) assessment at the time of angiography significantly improves outcome, but it has no apparent value as a routine study in all CAD patients, according to the randomized RIPCORD 2 trial. When compared to angiography alone in an all comer-strategy,
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Family bonds often run the deepest, which is why it’s all the more painful when they break down. Here, with the help of a counsellor, we explore how to navigate difficult family relationships Families: they’re not always easy. Separation, blended households, addictions, mental illness, money problems, betrayal, expectations, communication, or simply clashing personalities – there
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