Children

In a 2021 media statement released by the United States Centers for Disease Control and Prevention (CDC), the agency provided a series of updated guidelines on how the U.S. population can protect themselves and others from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC). Six months later, these guidelines still
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Antibodies that summon virus-engulfing white blood cells may play an important role in protecting infants from potentially serious congenital infection with human cytomegalovirus (HCMV), according to a study led by an investigator at Weill Cornell Medicine and NewYork-Presbyterian. The study, which appeared June 28 in the Journal of Clinical Investigation, was the most comprehensive analysis
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The transition to kindergarten is a notable milestone for children and families, who typically prepare by gathering school supplies and meeting the teacher. New research suggests that one important way to prepare for the transition to first-time schooling is to develop a bedtime routine in which children consistently get at least 10 hours of sleep
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While most people recover from COVID-19 within a week or two, up to one-third of survivors experience persistent or new symptoms weeks and months after initial infection. One form of “long COVID” is interstitial lung disease (ILD), a group of chronic pulmonary disorders characterized by inflammation and scarring (fibrosis) that make it hard for the
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A group of children’s hospitals from across the country will coordinate on the response to future pandemics and other disasters through a new $29 million grant from the Health Resources and Services Administration (HRSA). The group, known as the Pediatric Pandemic Network (PPN), will focus on the unique needs and challenges to children during pandemics
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A recent Children journal study examined neonates born to mothers infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and were admitted to the neonatal intensive care unit (NICU) as compared to neonates who remained with their mothers. Herein, the researchers confirm the rarity of SARS-CoV-2 vertical transmission and did not find a link between hospital outcomes
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In a qualitative, interview-based study of Emergency Department leaders, researchers at the University of Colorado Anschutz Medical Campus found most were motivated to provide high-quality pediatric sepsis care but disagreed on how best to do it. Pediatric sepsis is a time sensitive emergency, and a leading cause of pediatric morbidity and mortality. Preventing sepsis deaths
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Adding erythropoietin to cooling therapy for term newborns with birth asphyxia has no benefit over cooling therapy alone, a study published today in the New England Journal of Medicine. The findings contrast with results from small trials in which erythropoietin appeared safe and effective, noted Dr. Sandra “Sunny” Juul, senior author of the study. The
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Children born to mothers with polycystic ovary syndrome (PCOS) have an increased risk of developing infections, allergies and other childhood illnesses by the age of 13, according to the largest study to investigate this. The study, which is published today (Thursday) in Human Reproduction, one of the world’s leading reproductive medicine journals, looked at 1,038,375
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Today, the National Comprehensive Cancer Network® (NCCN®) published new NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Pediatric Central Nervous System (CNS) Cancers. This is now the fifth current NCCN Guidelines® to focus on childrens’ cancers, following recent publications of evidence-based, expert consensus guidelines for Pediatric Acute Lymphoblastic Leukemia, Pediatric Aggressive Mature B-Cell Lymphomas,
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Soon after its emergence at the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a devastating wave of infections, hospitalizations, and deaths throughout the world. The SARS-CoV-2 infection causes coronavirus disease 2019 (COVID-19), which is associated with a wide range of clinical features and an unpredictable prognosis. In a recent iScience
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Researchers at Saint Louis University’s School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver disease that formerly could only be treated with a liver transplant. The study, “Fazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency,” was published online in the New England
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For the most part, the bacterium Staphylococcus aureus is common and harmless, posing no threat to humans with whom they coexist. Occasionally, though, it can become an opportunistic pathogen, causing skin and bloodstream infections or food poisoning. For more than a century, scientists have searched for an effective vaccine, including at least 15 successful preclinical
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In a recent study posted to the medRxiv* preprint server, researchers determined the association between messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccinations and perinatal outcomes including congenital abnormalities, stillbirths, and premature births in Australia. Studies have reported that COVID-19 vaccination in pregnant women reduces stillbirths; however, the association between COVID-19 vaccines and premature
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Screening sperm may help identify potentially harmful new genetic mutations and help fertility specialists prevent them from being passed on to offspring, shows a preliminary study published in eLife. The results suggest a potential tool to help improve fertility treatment outcomes. New harmful disease-causing mutations can arise in sperm, and fathers may inadvertently pass them
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In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available. Study: Mechanistic model for booster doses effectiveness in healthy, cancer and immunosuppressed
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Sleep duration is now considered an essential component for ideal heart and brain health. Life’s Essential 8™ cardiovascular health score replaces Life’s Simple 7™, according to a new Presidential Advisory, Life’s Essential 8-;Updating and Enhancing the American Heart Association’s Construct on Cardiovascular Health, published today in Circulation, the Association’s flagship, peer-reviewed journal. Other updates to
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Researchers at UBC’s School of Biomedical Engineering have discovered that an existing cancer drug could have potential as a treatment for muscular dystrophy. Duchenne muscular dystrophy (DMD) is a severe genetic disorder that leads to progressive muscle weakness. Image Credit: University of British Columbia The researchers found that the drug — known as a colony-stimulating factor
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About 80% of people in the U.S. have low to moderate cardiovascular health based on the American Heart Association’s new Life’s Essential 8™ checklist according to a new study published today in Circulation, the Association’s flagship, peer-reviewed journal. Life’s Essential 8™, also published today in Circulation, details the Association’s updated guidance to measure cardiovascular health,
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In a June 27, 2022 announcement, the American Academy of Pediatrics (AAP) released new recommendations supporting mothers to continue breastfeeding for two years or beyond. These recommendations align with guidelines provided by the World Health Organization (WHO), the American Academy of Family Physicians (AAFP), and the Canadian Pediatric Society. Study: Breastfeeding and the Use of Human
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New research from UC Santa Cruz shows incremental improvements in the representation of autistic adults in film, television, books, media coverage, and advocacy organization websites. The study, published in the journal Autism in Adulthood, follows up on a 2011 paper, “Infantilizing Autism,” in Disability Studies Quarterly, which had found that popular portrayals of autism were
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