Clinical Trials & Research

NESS ZIONA, Israel, April 27, 2021 (GLOBE NEWSWIRE) — Sol-Gel Technologies, Ltd. (NASDAQ: SLGL), a clinical-stage dermatology company focused on identifying, developing and commercializing branded and generic topical drug products for the treatment of skin diseases, today announced an update regarding the U.S. Food and Drug Administration (FDA) approval process for Epsolay (benzoyl peroxide) 5%

Root Sciences and Ecodyst have joined forces to provide hi-speed evaporators to the market for solvent recovery in cannabinoid applications. Solvent recovery is a common bottleneck in many cannabis processing operations. The unique line of products manufactured by Ecodyst provides single equipment solutions for solvent recovery, decarboxylation, and devolatilization to prepare crude oil for molecular

KENILWORTH, N.J., & MIAMI–(BUSINESS WIRE) April 15, 2021 — Merck (NYSE: MRK), known as MSD outside the United States and Canada, and Ridgeback Biotherapeutics today provided an update on the clinical development program for molnupiravir (MK-4482/ EIDD-2801), an investigational orally available antiviral therapeutic. Based on a planned interim analysis of data from the Phase 2,

There are many different types of cancer, but they all have one thing in common: errors in the signals that control normal cell behavior can cause uncontrolled cell growth and cell division, leading to a tumor. An enzyme called SHP2 plays a key role in this regard. SHP2 is a signaling molecule that in its

KENILWORTH, N.J.–(BUSINESS WIRE) April 15, 2021 — Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced the discontinuation of development of MK-7110 (formerly known as CD24Fc) for the treatment of hospitalized patients with COVID-19. Merck acquired MK-7110 in December 2020 through its acquisition of OncoImmune, a privately-held clinical-stage biopharmaceutical company.

DeNovix Inc. announces the launch of EasyApps Secure, a 21 CFR Part 11 Compliance Ready software option for the DS-11 Series range of microvolume spectrophotometers and fluorometers. The new suite of controls for EasyApps software enables regulated labs to securely generate results within their compliant workflow while retaining the trademark ease of use associated with

INDIANAPOLIS, April 16, 2021 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) has requested the U.S. Food and Drug Administration (FDA) revoke the Emergency Use Authorization (EUA) for bamlanivimab (LY-CoV555) 700 mg alone. Lilly made this request due to the evolving variant landscape in the U.S. and the full availability of bamlanivimab and etesevimab together. This request

Several novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern have emerged since the inception of the pandemic. These variants often displaying enhanced infectiousness and virulence compared with wild-type strain. Whole genome sequencing is currently the gold standard in the identification and monitoring of these lineages. However, the set-up costs and operational requirements

April 16, 2021 — Today, the U.S. Food and Drug Administration revoked the emergency use authorization (EUA) that allowed for the investigational monoclonal antibody therapy bamlanivimab, when administered alone, to be used for the treatment of mild-to-moderate COVID-19 in adults and certain pediatric patients. Based on its ongoing analysis of emerging scientific data, specifically the

The airport says a lot about Cortez, Colorado: The single-engine planes that fly into its one-room airport seat nine passengers at most. The city of about 9,000 is known largely as a gateway to beautiful places like Mesa Verde National Park and the Four Corners Monument. But covid vaccines have made Cortez a destination in

TARRYTOWN, N.Y., April 12, 2021 /PRNewswire/ — Second Phase 3 trial undertaken in collaboration with NIAID to announce results today, both using subcutaneous administration of REGEN-COV in asymptomatic individuals without prior COVID-19 infection Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced positive data from a Phase 3 trial (2069B) of recently infected asymptomatic COVID-19 patients, evaluating REGEN-COV™ (casirivimab with

Today, the U.S. Food and Drug Administration approved Opdivo (nivolumab), in combination with certain types of chemotherapy, for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer and esophageal adenocarcinoma. This is the first FDA-approved immunotherapy for the first-line treatment of gastric cancer. Today’s approval is the first treatment in

April 13, 2021 — A clinical trial testing the safety and efficacy of an investigational monoclonal antibody for treating people who are hospitalized with respiratory disease and low blood oxygen due to infection with SARS-CoV-2, the virus that causes COVID-19, has begun. The Phase 2 trial, called the COVID-19 anti-CD14 Treatment Trial (CaTT), is sponsored

Apr 15 2021 Any future attempts to reduce the spread of covid-19 should be focused on tackling close airborne transmission of the virus which is considered to be the primary route for its circulation, according to experts in an editorial published in The BMJ. Respiratory experts argue that it is now clear that covid-19 (SARS-CoV-2)

News Clinical Trials Joint CDC and FDA Statement on Johnson & Johnson COVID-19 Vaccine April 13, 2021 — As of April 12, more than 6.8 million doses of the Johnson & Johnson (Janssen) vaccine have been administered in the U.S. CDC and FDA are reviewing data involving six reported U.S. cases of a rare and

Ziath has posted a new video that provides an easy-to-follow guide to assist scientists and technicians scanning and decoding sample tube racks direct from low temperature storage, especially when withdrawn from vapour phase liquid nitrogen tanks. The remove ice, blotting and scanning protocol is demonstrated to take less than 30 seconds per rack. The tracking

News Clinical Trials Johnson & Johnson Statement on U.S. COVID-19 Vaccine Manufacturing New Brunswick, NJ (April 3, 2021) – Johnson & Johnson is assuming full responsibility regarding the manufacturing of drug substance for its COVID-19 vaccine at the Emergent BioSolutions Inc. Bayview facility. Specifically, the Company is adding dedicated leaders for operations and quality, and significantly

Psychosocial stress – typically resulting from difficulty coping with challenging environments – may work synergistically to put women at significantly higher risk of developing coronary heart disease, according to a study by researchers at Drexel University’s Dornsife School of Public Health, recently published in the Journal of the American Heart Association. The study specifically suggests

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Apr. 7, 2021– Moderna, Inc. (Nasdaq: MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, today highlighted the publication of antibody persistence data out to 6 months following the second dose of the Moderna COVID-19 Vaccine in The New England Journal of Medicine. “We are pleased that this new data shows antibody persistence through 6 months following

Some studies have reported the detection of ribonucleic acid (RNA) specific for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in breast milk from women who were recently infected with the virus. A new study, released on the medRxiv* preprint server, explores the relationship between viral RNA and infectious virus to clarify the occurrence of

April 7, 2021 — A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines. A systemic allergic reaction to a vaccine occurs in one or more parts of the

Coronavirus disease 2019 (2019) is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen. Over a year into the COVID-19 pandemic, new variants of concern have emerged and posed serious health threats globally. These new variants have exhibited heightened transmissibility and immunity evasion. In a new study, published in the journal Cell,

NEW YORK & INDIANAPOLIS–(BUSINESS WIRE) March 25, 2021 — Pfizer Inc. (NYSE:PFE) and Eli Lilly and Company (NYSE:LLY) today announced the outcome of the U.S. Food and Drug Administration (FDA) Joint Arthritis Advisory Committee and Drug Safety and Risk Management Advisory Committee on tanezumab. There was a single voting question focused on whether the proposed

Apr 5 2021 A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of the most common causes of disability and death. Stephen S. Rich, PhD,

MADRID, SPAIN and CAMBRIDGE, MA, UNITED STATES, March 29th, 2021 - Oryzon Genomics, S.A. (ISIN Code: ES0167733015, ORY), a clinical-stage biopharmaceutical company leveraging epigenetics to develop therapies in diseases with strong unmet medical need, announced today the enrollment of the first patient in the PORTICO Phase IIb clinical trial with vafidemstat in Borderline Personality Disorder (BPD),

Deprivation among society at large is ‘driving’ Covid-19 disparities among minority ethnic groups – predominantly South Asian and Black African or Caribbean populations – and could be considered the main cause of disproportionate infection rates, hospitalization and deaths experienced by these populations, according to new analysis from the University of Leicester. The study, supported by

HOUSTON, March 30, 2021 /PRNewswire/ – Moleculin Biotech, Inc., (Nasdaq: MBRX) (Moleculin or the Company), a clinical stage pharmaceutical company with a broad portfolio of drug candidates targeting highly resistant tumors and viruses, today announced that the U.S. Food and Drug Administration (“FDA”) has approved its request for Fast Track Designation for its drug, Annamycin, for

Following recent U.S. Food and Drug Administration actions to support test development, the FDA took swift action this week to get more tests for screening asymptomatic individuals on the market. Today, the agency authorized several tests for over-the-counter (OTC) use without a prescription when used for serial screening. In addition to the tests authorized for