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The discovery of athletes developing myocarditis after battling a COVID-19 infection previously forced several professional and collegiate sports leagues to cancel their major events and seasons. But latest scientific data on the pathogenesis of the coronavirus disease has shed light on how the incidence of heart inflammation among athletes was lower than first thought.  New

PHOENIX — The addition of pembrolizumab (Keytruda) to chemotherapy, with or without bevacizumab (Avastin), in women with persistent, recurrent, or metastatic cervical cancer was linked with better quality of life (QoL), a researcher reported. Patient-reported outcomes (PRO) from the KEYNOTE-826 trial showed that changes from baseline in QLQ-C30 global health status (GHS)/QoL scores — a

The FDA tonight approved a combination nivolumab/relatlimab-rmbw immune checkpoint inhibitor (Opdualag) for unresectable or metastatic melanoma in adults and children 12 years or older, according to the drug’s manufacturer, Bristol-Myers Squibb.  Approval was based on the company’s RELATIVITY-047 trial, which found a median progression-free survival (PFS) of 10.1 months among 355 patients randomly assigned to

A study released by the Centers for Disease Control and Prevention found that the Omicron variant of COVID-19 led to an increased rate of hospitalization in children below the age of 4, which was five times higher than the spread of the Delta variant, according to WebMD.  “COVID-19 can cause severe illness in infants and children,” the CDC said, adding that “COVID-19–associated

In children, the rare disorder cold urticaria (coldU) tends to persist for years and carry an elevated risk for anaphylaxis, a study from Canada reports. ColdU often affects young adults but can occur at any age. “Data on coldU in children are sparse,” the authors write in Pediatric Allergy and Immunology. For people with coldU,

A study published Wednesday in the New England Journal of Medicine found that a fourth dose of the COVID-19 vaccine is “somewhat efficacious,” but still “immunogenic” and “safe.” Authors of the study wrote that there was no significant difference in immune response or “in levels of omicron-specific neutralizing antibodies” between a third and fourth dose

A novel open-label, phase II trial recently published in the Journal of Clinical Oncology evaluated the safety and efficacy of balstilimab co-administered with zalifrelimab as second-line treatment for 155 patients with recurrent and/or metastatic cervical cancer who had relapsed after prior platinum-based therapy. In this exclusive MedPage Today interview, Robert DeBernardo, MD, section head of

A fourth dose of the mRNA vaccines did not provide better protection against COVID-19 transmission than vaccination with three doses, researchers said in a new study.  Efficacy Of A Fourth Dose In a study published in The New England Journal of Medicine Wednesday, scientists reported their findings after examining the efficacy of the fourth dose

New data released by Biogen this week show that long-term treatment with aducanumab (Aduhelm) continues to reduce the underlying pathologies of Alzheimer’s disease (AD) after more than 2 years of treatment. Patients receiving aducanumab in the long-term extension phase of two phase 3 trials (ENGAGE and EMERGE) continued to experience significant reductions in amyloid beta

It may feel like a long time ago, but it’s only nine months since the UK was in the grips of the “pingdemic”. Back in the summer of 2021, lifting COVID restrictions saw the country’s contact-tracing apps – the NHS COVID-19 app in England and Wales, the StopCOVID NI app in Northern Ireland, and the

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A new surge in COVID-19 cases across Western Europe has led U.S. health officials to consider whether another pandemic wave will arrive soon, even as states and cities continue to lift restrictions amid low case numbers. Infectious disease experts are watching

In patients with osteoarthritis (OA) of the knee, intra-articular injections of steroids did not increase rates of either disease progression or subsequent knee replacement surgery, researchers said. Among more than 560 OA patients in a long-running French cohort, 6.0% of those receiving steroid injections underwent knee replacement within 5 years, compared with 6.4% of patients

A study published Monday with the Lancet medical journal found that people who were bedridden for 7 days or more with COVID-19 were more likely to experience anxiety and depression a year after their diagnosis. “Our findings are in line with the limited existing literature on both inpatients and outpatients, indicating a link between COVID-19 diagnosis

A population-based developmental surveillance program showed high diagnostic accuracy in identifying autism in a community-based sample of infants, toddlers, and preschoolers, according to new data published online in JAMA Network Open. Researchers, led by Josephine Barbaro, PhD, of Olga Tennison Autism Research Centre at La Trobe University, Bundoora, Australia, said their findings indicate the benefit of

The doctors and dentists Americans count on are still fuelling the opioid crisis. Big pharma pushes addictive drugs, and our healthcare system is more than happy to pay for them. We won’t win this battle by dishing out more prescriptions. Instead, we have to fundamentally reframe the way we view pain and addiction.   Pain

The study covered in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaways In a study of a longitudinal cohort of patients with Parkinson’s disease (PD) off therapy, the sequence effect was measured using best-fit decay of angular velocity, an objective metric of limb bradykinesia, and

A survey published last month in the Journal of Allergy and Clinical Immunology looked at training programs in allergy and immunology to assess the current curriculum and gaps in health disparities and health equity education. The study was also presented at the American Academy of Allergy, Asthma & Immunology (AAAAI) annual meeting by Nicole Ramsey,

Depression, anxiety, and other mental health issues could be the most intriguing long-term effects of severe COVID-19. A new study found that bedridden patients were at high risk for these conditions that could linger for years after their bout with SARS-CoV-2. COVID-19 And Mental Health  In a study published in The Lancet Public Health journal

Among patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorders (NMOSD) receiving ocrelizumab or rituximab, B cell depletion appears to last well past the 6-month dosing regimen typically used with these drugs. The results, drawn from a retrospective analysis, provide support for clinical trials to rest longer re-infusion intervals. Dr Mahmoud AbdelRazek The study appeared online Jan.

The following is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that has yet to be certified by peer review. One in four kids with COVID develop lingering problems One in four children with COVID-19 symptoms develop “long COVID,” according to data pooled

In casual conversation these days, you’re likely to hear: “I’m just done with COVID.” The problem is the virus isn’t done with us, yet. Nor is Ukraine, inflation, or nuclear threats, to name a few. The statistics 2 years into the pandemic are sobering, or should be. Deaths from COVID-19 in the United States are

Use of advanced preoperative 3D planning for pediatric liver transplant patients receiving larger grafts was associated with lower risk of postoperative complications, a small retrospective study in Taiwan found. Kids receiving living-donor livers that were large-for-size — graft-to-recipient weight ratio (GRWR) ≥4% — had a significantly lower risk for postoperative complications in the 3D era

A new expert commentary from the American Gastroenterological Association focuses on noninvasive screening options for colorectal cancer (CRC), as well as approaches to ensure quality in noninvasive screening programs. The commentary was published in Gastroenterology. The American Cancer Society reported in its Cancer Facts & Figures 2021 report that lifetime risk of CRC in the United States is 4%,

Deltacron, a coronavirus recombinant that contains genes from both the Delta and Omicron variants, has been confirmed as a variant of the COVID-19 virus after first being discovered in January. The first solid evidence of Deltacron was shared by the Institut Pasteur in France, though GISAID said that “further investigations are needed to determine if

The US Food and Drug Administration (FDA) has issued a warning about the off-label use of the Renuvion/J-Plasma device for dermal resurfacing and skin contraction procedures. The device is cleared by the FDA for “general use of cutting, coagulation, and ablation of soft tissue during open and laparoscopic surgical procedures” but “has not been determined

In this video, Matthew Wynia, MD, MPH, of the University of Colorado’s Anschutz Medical Campus in Aurora, discusses his article in the Annals of Internal Medicine on the ethics of treating hunger-striking detainees and gives advice to physicians who may be pressured to make difficult ethical decisions. The following is a transcript of his remarks:

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. It’s now known that tinnitus may be an unexpected side effect of SARS-CoV-2 vaccination, and there is an urgent need to understand the precise mechanisms and best treatment for vaccine-associated tinnitus, researchers say. As of mid-September 2021, 12,247 cases of tinnitus,

Researchers have developed a huggable cushion device that mimics breathing, and it has been found to be as effective as guided meditation in easing anxiety in a preliminary study. About a third of people are affected by anxiety disorders in their lifetime, according to the authors of a new paper published in PLOS ONE. In fact, anxiety disorders