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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. It was supposed to be a turning point in the coronavirus pandemic for Erin Tokley, a longtime Philadelphia police officer, Baptist minister and 47-year-old father of three. It was supposed to be the day of his vaccine appointment. Instead it was
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In the early days of the pandemic, scientists have already established that the younger population is not really affected by COVID-19 because of the difference in their immune system compared to adults. However, children are still at risk since they can get infected with the novel coronavirus. This urged government leaders and medical experts to
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A novel liquid biopsy test has been shown to distinguish between patients with neurofibromatosis type 1 (NF1) who have benign plexiform neurofibroma (PN) precursor lesions from patients who have malignant peripheral nerve sheath tumors (MPNST), say authors of a multi-institutional cross-sectional study. “Transformation from PN to MPNST is challenging to detect by imaging…or by biopsy…which
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A “quadpill” containing quarter doses of four blood pressure (BP)-lowering medications was more effective than monotherapy for initial treatment of hypertension, with similar tolerability, in the 1-year, phase 3 QUARTET randomized, active-control trial. Clara Chow, MD, PhD, academic director of the Westmead Applied Research Centre, University of Sydney, Australia, presented the findings in a late-breaking trial
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The cerebral venous thrombosis (CVT) that occurs as part of the rare adverse reaction to the adenovirus vector COVID-19 vaccines from Astra Zeneca and Johnson & Johnson is much more severe and associated with greater mortality and disability than sporadic CVT,
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Serious health risks were no more common in the first 3 weeks after Pfizer/BioNTech or Moderna COVID-19 vaccination compared with 22-42 days later, a first-of-its-kind study of more than 6 million people reveals. mRNA vaccination was not associated with greater risks
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From face masks to hand sanitizers and disinfecting sprays, there’s no shortage of “essential items” that are being marketed as able to help protect us from COVID-19. According to experts, another item that people should add to their list of essentials is an air purifier. The best air purifiers can help a lot in eliminating dust, pollen, smoke and other
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Greater short-term variability in systolic blood pressure after intracerebral hemorrhage (ICH) is associated with an increased risk for long-term disability, new research suggests. A pooled analysis of randomized controlled trials indicated that each 10 mmHg increase in standard deviation of systolic blood pressure variability was associated with an 18% increase in the likelihood of functional
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An FDA advisory committee offered up lower vector doses, stricter exclusion criteria, and long-term animal studies to grapple with liver toxicities associated with adeno-associated virus (AAV) vector-based gene therapies. During the second of four sessions on AAV safety, the Cellular, Tissue, and Gene Therapies Advisory Committee (CTGTAC) weighed evidence of hepatotoxicity — ranging from liver
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In patients with moderate to severe ulcerative colitis (UC), treatment with vedolizumab leads to better histologic outcomes than treatment with adalimumab, according to findings from the VARSITY trial. The findings come from an analysis in Gastroenterology of prespecified histologic exploratory endpoints from the phase 3, multicenter, randomized, controlled VARSITY trial, which was the first head-to-head comparison of
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While more and more people are getting vaccinated against COVID-19, the US’ daily infection rate is on the rise, prompting the Centers for Disease Control and Prevention (CDC) to recommend the continued use of face masks whether they are vaccinated or not. The Delta Variant According to the CDC, the Delta variant is currently the predominant strain of the coronavirus in
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Last year, Katherine Gill, MD, an HIV prevention researcher in Cape Town, South Africa, realized how jaded she’d become to vaccine research when the Pfizer COVID-19 vaccine came back as 95% effective. In her career conducting HIV clinical trials, she’d never seen anything like it. Even HIV prevention methods she had studied that had worked,
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A safe and minimally invasive implanted stimulation device is getting mostly positive reviews from neurosurgeons, with some experts saying it represents a “paradigm shift” in the treatment of mechanical low back pain. Results from a multicountry study show that the ReActiv8 device (Mainstay Medical Limited) is efficacious, improving function and reducing pain for up to
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Paralympian swimmer Jessica Long was born with bilateral fibular hemimelia, a congenital shortening or absence of the fibula. If you watched any of the Tokyo Olympics, you were no doubt moved by a commercial from Toyota that featured Long, depicting a phone call to her parents about a baby they are going to adopt from
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Did you know that there are over 100 trillion microorganisms in our body? Most of these microorganisms are gut-living good bacteria that work to fight off the bad bacteria and restore balance in our bodies to make us feel better. Unfortunately, there are times when our gut becomes unbalanced with unhealthy levels of certain bacteria causing
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For years, people have enjoyed drinking energy drinks, especially after an intense workout to “replenish” their lost electrolytes. But what are electrolytes? These are minerals (calcium, sodium, potassium, magnesium, chloride, phosphate) that help maintain our body’s ionic balance. When we exercise, we sweat a lot, so we need to replenish the electrolytes lost to avoid dehydration and exhaustion. When we exercise, we end up
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