Children

CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma. However, Black and Hispanic people were largely absent from the major clinical trials that led to the U.S. Food and Drug Administration approval
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Women’s elevated anxiety, depression and stress during pregnancy altered key features of the fetal brain, which subsequently decreased their offspring’s cognitive development at 18 months. These changes also increased internalizing and dysregulation behaviors, according to a new study by Children’s National Hospital published in JAMA Network Open. Researchers followed a cohort of 97 pregnant women
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Young adults who received organ transplants as children may not be regularly attending their doctor appointments after leaving their pediatric providers. Missing these appointments is associated with longer and more frequent hospitalizations and poorer medication adherence, according to a new study. Researchers at the University of Georgia found a significant decline in attending adult health
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The National Institutes of Health (NIH) recently awarded a Phase 1, 5-year $10.9 million Center of Biomedical Research Excellence (COBRE) award, entitled Research Expanding Access to Child Health (REACH) Center to Anne Kazak, PhD, Enterprise Director, and Melissa Alderfer, PhD, Director of the Center for Healthcare and Delivery Science (CHDS) at Nemours Children’s Health. It
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Roswell Park Comprehensive Cancer Center specialists will share the latest advances and developments in the treatment of blood-related cancers at the 2022 Tandem Transplantation & Cellular Therapy Meetings of the American Society for Transplantation and Cellular Therapy (ASTCT) and Center for International Blood and Marrow Transplant Research (CIBMTR) in Salt Lake City, Utah, from April
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A new study describes the impact of the COVID-19 pandemic on pediatric primary care mental health visits. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2022 Meeting, taking place April 21-25 in Denver. Researchers with Boston Children’s Hospital found that visits to pediatric primary care offices for eating disorder and
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A new study reports that selective impairments in regional fetal brain growth predict adverse cognitive, language and motor outcomes in infants with congenital heart disease. Interestingly, larger fetal ventricular volumes were associated with early autistic features. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2022 Meeting, taking place April 21-25
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A new study demonstrates that intranasal human milk is a safe and feasible intervention for intraventricular hemorrhage, a serious cause of morbidity in preterm infants. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2022 Meeting, taking place April 21-25 in Denver. This is the first prospective trial on safety and
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Thought LeadersDr. Zhaoming WangEpidemiology & Cancer ControlSt. Jude Children’s Research Hospital In this interview, we speak to Dr. Zhaoming Wang about his latest research that investigated accelerated aging in childhood cancer survivors and the underlying genetics causing this. Please could you introduce yourself and tell us what inspired your latest research? I’m an associate member
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Abnormalities in a type of brain cell called astrocytes may play a pivotal role in causing some behavioral symptoms of autism spectrum disorders, according to a preclinical study by Weill Cornell Medicine investigators. For the study, published April 1 in Molecular Psychiatry, senior author Dr. Dilek Colak, assistant professor of neuroscience at the Feil Family
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New study demonstrates that in utero exposure to mother’s antiepileptic or antidepressant medication may affect development of the newborn brain networks. In the study, novel mathematical methods were developed to allow future research on how commonly used drugs or other environmental conditions affect the newborn brain. Pregnant mothers may need treatment for their medical conditions,
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In the current phase of the coronavirus disease 2019 (COVID-19) pandemic, a new study, published in the Journal of Pediatrics and Child Health, shows that the infection is not typically transferred to newborns from infected mothers, and if such transmission occurs, the resulting disease is usually mild. This knowledge could help shape better practices in such settings to
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A free youth development program serving Black children and teens living in a low-income segregated community demonstrated positive long-term educational and financial outcomes in its alumni, according to a study from Ann & Robert H. Lurie Children’s Hospital of Chicago published in the journal BMC Public Health. A 33-year follow-up revealed that alumni graduated from
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A study released today indicates that SARS-CoV-2 (COVID-19) spreads extensively in households, with children being a significant source of that spread. Approximately 50% of household members were infected from the first-infected individual during the study period. Although kids were less likely to spread the virus compared to adults, children and adults were equally likely to
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A woman’s exposure to pesticides during pregnancy could lead to differences in sleep duration and timing during adolescence for her female offspring, according to a new University of Michigan study. While non-occupational pesticide exposure is widely known to occur through chemical products used to repel insects in the home, exposure can also occur through other
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A hormone that triggers puberty and controls fertility in humans might be developed as a treatment for non-alcoholic fatty liver disease, according to new Rutgers research. The study, appearing in the Journal of Clinical Investigation, provides powerful evidence that a modified version of the naturally occurring hormone kisspeptin can be used to treat non-alcoholic fatty
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Five childhood risk factors that predict stroke and heart attacks in adulthood have been identified after being tracked for up to half a century in the world’s largest international prospective cardiovascular disease study. The study, conducted by the International Childhood Cardiovascular Consortium (i3C) including researchers from the Murdoch Children Research Institute (MCRI), found body mass
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An international report with recommendations designed to counteract school-related sedentary behavior in children and youth, exacerbated by COVID-19 pandemic restrictions, has been released by the Sedentary Behaviour Research Network (SBRN), in partnership with the University of Prince Edward Island and the CHEO Research Institute. The report, International School-Related Sedentary Behaviour Recommendations for Children and Youth,
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