Children

Poor heart health, especially among women of color, puts both mothers-to-be and their infants at risk, with heart disease causing more than one in four pregnancy-related deaths (26.5%) in the U.S., according to the American Heart Association Heart Disease and Stroke Statistics 2022 Update. To address this growing concern, the American Heart Association has announced
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Nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled Phase 3 clinical trial. It is the first potential immunization against RSV in the general infant population, with a single dose providing safe protection across the entire RSV
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Researchers from the Mitochondrial Medicine Frontier Program at Children’s Hospital of Philadelphia (CHOP) have found that developmental delays associated with Leigh syndrome, the most common pediatric mitochondrial disorder, may occur earlier than previously recognized – even before metabolic stroke and regression – which could provide clinicians with an opportunity for earlier diagnosis and therapeutic interventions.
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Antibiotics provide no benefit in preventing future recurrent wheezing in babies hospitalized with respiratory syncytial virus (RSV), according to a new study led by Washington University School of Medicine in St. Louis. And there is some evidence that antibiotics may make wheezing worse. The antibiotic azithromycin has anti-inflammatory properties that can be beneficial in some
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Post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is estimated to affect about 2% of the population in the United Kingdom (UK). These long-term symptoms of coronavirus disease 2019 (COVID-19), also called post-acute COVID-19 syndrome, post-COVID-19 syndrome, long COVID, or post-COVID condition, cause functional impairment in the majority of those affected. COVID-19
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As a clinician at the University of Missouri Thompson Center for Autism and Neurodevelopmental Disorders, David Beversdorf helps patients with autism spectrum disorder (ASD), many of whom may also be struggling with gastrointestinal or digestive issues, including constipation and diarrhea. These symptoms are experienced by children with ASD at a higher rate than their neurotypical
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Intersectionality posits that social categorizations and personal identities are interconnected in a way that creates a unique nuanced lived experience for individuals rather than an additive experience. For example the experience of a queer Black woman living in a rural area is not the sum of being queer, Black, and in a rural location, as
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The novel severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) primarily triggers an immune condition that affects multiple organ systems. The intensity of sickness is connected to the individual’s primary immunological response and relies on age and comorbidities. The danger of re-infection is determined by the quality of the long-term immune response. However, detailed immunological knowledge
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Over 90 percent of patients with transfusion-dependent thalassemia, an inherited blood disorder, no longer needed monthly blood transfusions years after receiving gene therapy, according to an international Phase 3 clinical trial that for the first time included children younger than 12 years of age. Twenty-two patients were evaluated (ranging in age 4-34 years), including pediatric
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The experiences children have at a young age help form their identity and relationships with the natural world-;and where they grow up impacts that environmental identity and sense of place, according to South Dakota State University associate professor Carie Green. She is examining how family, culture and geographical location shape the way in which children
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The current trend of using two cannulas to place most newborns in respiratory failure on life-sustaining ECMO, one in the right internal jugular vein and a second in the right common carotid artery, rather than a single cannula in the right internal jugular, increases mortality rates for these babies, investigators report. Their assessment of nearly
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Brain organization differs between boys and girls with autism, according to a new study from the Stanford University School of Medicine. The differences, identified by analyzing hundreds of brain scans with artificial intelligence techniques, were unique to autism and not found in typically developing boys and girls. The research helps explain why autism symptoms differ
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In a recent study posted to the medRxiv* preprint server, researchers from the United States assess the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough cases and reinfections among unvaccinated and vaccinated individuals. Study: Time to reinfection and vaccine breakthrough SARS-CoV-2 infections: a retrospective cohort study. Image Credit: PhotobyTawat / Shutterstock.com Introduction To date,
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The University of South Florida recently received a highly competitive National Institutes of Health (NIH) Institutional Training Grant (Award Number T32HL160529), boosting the USF Health Morsani College of Medicine’s (MCOM) capacity to prepare the next generation of scientists in an emerging area of research applicable to many major diseases. The NIH’s National, Heart, Lung, and
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In most developed countries, several vaccines have been developed against the coronavirus disease 2019 (COVID-19), all of which target the immunodominant spike antigen of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A new JAMA study discusses the antibody levels in the newborns born from mothers who have been vaccinated against COVID-19 and compares these levels
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In a research paper posted to the Research Square preprint* server and under consideration for publication in the European Journal of Pediatrics journal, researchers assess the different clinical symptoms of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and adolescents across different time periods. Study: Dynamics in COVID-19 Symptoms During Different Waves of
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A recent research letter published in the JAMA demonstrated the prevalence and the longevity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in coronavirus disease 2019 (COVID-19) unvaccinated United States (US) adults recovered from the disease in the long term. Research Letter: Prevalence and Durability of SARS-CoV-2 Antibodies Among Unvaccinated US Adults by History
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