Children

Northwestern Medicine investigators continue to study the COVID-19 pandemic, from the biological mechanisms of disease and infection patterns to the pandemic’s impact on women and sexual and gender minorities. Outcomes of COVID-positive youths at emergency departments Among 3,221 youths who tested positive for SARS-CoV-2, the virus that causes COVID-19, in emergency departments (EDs), 3.3 percent

Fathers older than age 34 were more open to having their child vaccinated against COVID-19, while younger Black and white mothers were the least open to it, finds a new survey of Medicaid recipients from the Brown School at Washington University in St. Louis. Helping younger parents in all ways should be a priority. They

A novel gene therapy promoted transfusion independence in more than 90 percent of adult and pediatric patients with transfusion-dependent beta-thalassemia, according to a recent clinical trial published in The New England Journal of Medicine. The therapy represents a potentially curative treatment option for patients who must otherwise rely on life-long red blood cell transfusions. This

New research from the Institute of Psychiatry, Psychology, & Neuroscience (IoPPN) at King’s College London has found that young people who experience loneliness during early adolescence (age 12) are at greater risk of leaving school with lower grades than their non-lonely counterparts, even if they stop being lonely later on. The study, published in Development

Pain-predominant disorders of gut-brain interaction (DGBIs) in children -; such as functional abdominal pain (FAP) and irritable bowel syndrome (IBS)-; can lead to disabling symptoms, poor quality of life and high use of health care resources. Studies suggest that an open-label placebo (OLP) approach -; in which patients are aware that they are receiving a

Purchases of sugary drinks could be reduced by pictorial health warnings, reports research publishing February 1st in the open access journal PLOS Medicine. A trial in a naturalistic store setting found parents bought fewer sugary drinks when products displayed pictorial warnings about type 2 diabetes or heart damage, as compared with barcode labels. The study

Fusion oncogenes, such as RET- and NTRK-gene fusions, are associated with more invasive pediatric thyroid cancers, correlating with the highest risk of metastases and a lower likelihood of achieving remission one year after initial therapy, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP). The findings, which were published in the

Jan 29 2022 Children in care who come from an ethnic minority background can experience a ‘double whammy’ of disadvantage when it comes to youth justice involvement, says new research from Lancaster University. Inequalities in the youth justice system regarding ethnic minority children and children in care, including foster care, children’s homes or kinship care,

In-hospital addiction medicine consultations can reduce deaths in high-risk patients with substance use disorder, according to a new study published in the Journal of General Internal Medicine by University of Pittsburgh physicians. This research is among the first of its kind to show these consults are a life-saving intervention. In this past year, more people

As of January 27, 2022, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 366 million worldwide and caused over 5.6 million deaths. Several reports confirm that those over the age of 65 are at a greater risk of SARS-CoV-2 infections. Study: Loss of Pfizer (BNT162b2) Vaccine-Induced Antibody Responses against the SARS-CoV-2 2

A study published in the journal Immunity analyzed the varied manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children. Introduction Among the different SARS-CoV-2 variants of concern (VOCs), the severity of Coronavirus disease 2019 (COVID-19) in adults is high, while children and young adults are not as severely impacted. Furthermore, various other viruses

PIK3CA-related overgrowth spectrum (PROS) is a group of rare, incurable disorders caused by mutations in the PIK3CA gene that result in the malformation and overgrowth of various parts of the body. A new report to be published January 26 in the Journal of Experimental Medicine (JEM) describes the successful treatment of two young infants with

About a fifth of young sexual minority males and transgender females are estimated to be engaging in transactional, or survival sex, according to results of a new survey study by Johns Hopkins Medicine researchers. The findings, which define the practice as trading sex for money, housing and other necessities (e.g., food, clothing), were published in

Thousands of schools transitioned to online learning in 2020 due to the COVID-19 pandemic, during which time many children with cancer and other chronic health needs, as well as those with special education needs, faced significant challenges to learning online. An opinion paper by Johns Hopkins experts, published Jan. 4 in the journal JAMA Pediatrics,

Of hospitalized children who tested or were presumed positive for SARS-CoV-2, 44% developed neurological symptoms, and these kids were more likely to require intensive care than their peers who didn’t experience such symptoms, according to a new study led by a pediatrician-scientist at UPMC and the University of Pittsburgh School of Medicine. The most common

Children’s Hospital Colorado (Children’s Colorado) released a study today that examines the efficacy of a neuromuscular training (NMT) intervention that may lead to new treatment approaches and better outcomes for athletes when they return to playing sports after a sports-related concussion. While preliminary, the findings indicate the risk of sports-related injuries for the year after

A clinical trial funded by the National Institutes of Health has found that giving peanut oral immunotherapy to highly peanut-allergic children ages 1 to 3 years safely desensitized most of them to peanut and induced remission of peanut allergy in one-fifth. The immunotherapy consisted of a daily oral dose of peanut flour for 2.5 years.

The majority of young children treated with peanut immunotherapy achieved desensitization after two and a half years of treatment, and one in five remained in remission 26 weeks after treatment ended, according to a randomized controlled trial published in The Lancet. Achieving remission was more common the younger the child was at the start of

An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, according to a new study in mice from Washington University School of Medicine in St. Louis. Shown are sections of liver from mice on a high-fat, high-sugar diet. On the left, more white space indicates greater

Babies born in cities are surprisingly at increased risk of death in their first month of life compared with their counterparts in rural areas in Tanzania, a study says. In 2019, for every 1,000 live births in Sub-Saharan Africa, 27 were more likely to die within the first month of life, a rate that was

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls. Published in Cell Reports, this is the first time that vascular endothelial cells could be reached for genome editing, since the usual way to deliver CRISPR/Cas9 – through a virus – does not

In a large prospective study of just over 1,000 patients ages 17 and younger who were seen at the Baltimore Convention Center Field Hospital (BCCFH) testing site during a seven-month period last year, researchers from Johns Hopkins Medicine and collaborating institutions report that a rapid antigen test for SARS-CoV-2 — the virus that causes COVID-19

Two months after Pfizer’s covid vaccine was authorized for children ages 5 to 11, just 27% have received at least one shot, according to Jan. 12 data from the Centers for Disease Control and Prevention. Only 18%, or 5 million kids, have both doses. The national effort to vaccinate children has stalled even as the

Scientists have worked at an unprecedented speed to develop vaccines to fight against the ongoing coronavirus disease 2019 (COVID-19) pandemic. This pandemic has been caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus belonging to the family Coronaviridae. Study: Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. Image Credit: NIAID Background It

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours -; a feat that’s nearly unheard of in standard clinical care. “A few weeks is what most clinicians call ‘rapid’ when it comes to sequencing a patient’s genome

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is undergoing repeated and extensive mutational changes that have led to the emergence of several variants of concern (VOC) that often show higher transmissibility and immune-evasion characteristics. Among these VOCs include the Delta variant, which played a major role in the most recent wave of infections, hospitalizations,

A new international study offers a clearer picture of the impact of COVID-19 infection and the risk of severe outcomes on young people around the world. The study was co-led by a team of researchers from the University of Calgary’s Cumming School of Medicine (CSM), Ann & Robert H. Lurie Children’s Hospital of Chicago, and

Researchers at Washington University School of Medicine in St. Louis have received three grants totaling more than $6.8 million to advance research on a novel imaging system to monitor uterine contractions. The electromyometrial imaging system, called EMMI, was invented and developed at Washington University. The device allows physicians to measure, in 3D, the electrical activity