Children

An immunotherapy harnessing the immune system’s “natural killer” cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return. Now, researchers at Washington University School of Medicine in St. Louis have shown, in a small clinical trial, that the same natural killer cells also can help some children and young

For many emerging adults, the period between 18 and 25 years of age marks a stage of life to explore what matters to them and assume new legal rights and responsibilities, including their own private health information and medical decision-making. But this transition to independence can create sticky family dynamics, especially when emerging adults remain

Adapted with permission from the American Heart Association. Most young people under the age of 21 who developed suspected COVID-19 vaccine-related heart muscle inflammation known as myocarditis had mild symptoms that improved quickly, according to new research published today in the American Heart Association’s flagship journal Circulation. Myocarditis is a rare but serious condition that

A new medication has been added to the treatment options for children with moderate-to-severe asthma. In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11. The findings of the international multicenter Liberty Asthma VOYAGE trial, reported

In a concerning trend for the health of U.S. children, the rate of underinsured youngsters rose from 30.6% to 34%- an additional 2.4 million kids- from 2016 to 2019, according to an analysis led by University of Pittsburgh School of Medicine researchers. In the study, published today in Pediatrics, the researchers found that underinsurance of

Young people aged 12 to 18 are unlikely to report receiving, or being asked to share, non-consensual sexual images to their school, parents or social media platforms such as Snapchat, TikTok and Instagram, finds a major new report led by UCL. The findings, launched today by the UCL Institute of Education, the University of Kent,

Autism prevalence among 8-year-old Utah children has risen by nearly 30% in less than a decade, according to a study of 11 communities nationwide, including Salt Lake City and surrounding counties, led by the Centers for Disease Control and Prevention (CDC). Autism prevalence among 8-year-olds in the state rose from 1 in 58 children in

When a child has a fever, their body can ache, they are restless and they just don’t feel well. While a fever is a part of our natural response to infection, the fever itself can lead to complications. One rare complication is a febrile seizure. A febrile seizure is when your child (ages 6 months

A bacterium common in the mouse gut microbiome can charge up the immune system to fight cancer cells in the colon, researchers from the University of Pittsburgh School of Medicine report today in the journal Immunity. The study showed that bacterium Helicobacter hepaticus boosted adaptive immune response and prompted selective activation of Helper T cells

Babies born to women with anemia during pregnancy have an increased risk of childhood anemia, according to a study carried out in rural India. Anemia, characterized by less than normal concentration of hemoglobin (Hb) in the blood, is an important public health challenge with a prevalence rate of 47 per cent among non-pregnant women and

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive. Journal in Which the Study was Published: Blood Cancer Discovery, a journal of the American

In the first MRI-based study to investigate pre-natal alcohol exposure, researchers found significant changes in the brain structure of fetuses exposed to alcohol compared to healthy controls. Results of the study are being presented today at the annual meeting of the Radiological Society of North America (RSNA). Fetal alcohol syndrome is a worldwide problem in

Saliva samples are easy to obtain and useful for measuring antibodies to SARS-CoV-2 in children, which could facilitate epidemiological surveillance in school settings. The study, a collaboration between the Barcelona Institute for Global Health (ISGlobal), an institution supported by “la Caixa” Foundation, and the Hospital Sant Joan de Déu (HSJD), followed over 1,500 children who

A team of UK-based scientists has recently evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in preventing household transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in England. Their findings indicate that the vaccines effectively reduce transmission of SARS-CoV-2 alpha and delta variants from breakthrough infections in the household setting, despite having reduced

Weill Cornell Medicine has received a $1.27 million grant from the United States Department of Defense (DoD) to develop treatment for a rare but devastating eye condition largely affecting military personnel who suffer traumatic eye injuries in combat. Under the three-year grant, investigators will test the safety and effectiveness of two newly developed antibodies to

Quarraisha Abdool Karim has spent the past three decades studying HIV and AIDS. She has become one of the world’s leading epidemiologists and made major contributions to the global understanding of how HIV affects young women. As associate scientific director of the Centre for the AIDS Programme of Research in South Africa (CAPRISA), Abdool Karim

Washington University in St. Louis is joining a major international effort to advance data science, catalyze innovation and spur health discoveries across Africa. Researchers at the School of Medicine are receiving one of 19 grant awards that will support data science research and training activities in Africa. The researchers will focus their efforts on developing

The perception of gender in children’s voices is of special interest to researchers, because voices of young boys and girls are very similar before the age of puberty. Adult male and female voices are often quite different acoustically, making gender identification fairly easy. Gender perception is much more complicated in children because gender differences in

Cynthia Rogers, MD, visits a baby in the Newborn Intensive Care Unit at St. Louis Children’s Hospital. Rogers is helping lead a national study aimed at understanding how prenatal factors and early life experiences influence brain development and behavior in infants and young children. Researchers at Washington University School of Medicine in St. Louis are

A new study summarized in a research letter published in JAMA Pediatrics reveals that a number of factors, including negative impacts from the pandemic during pregnancy, health care experiences, and reports of discrimination, made it less likely that infants received their recommended vaccinations in the first months of their lives. Led by Heidi Preis, MSW,

A recent study found that the drug tranexamic acid has minimal impact in controlling blood loss in severely injured trauma patients at the standard doses given, according to researchers at Washington University School of Medicine in St. Louis. The drug, also called TXA, is routinely given at many hospitals across the U.S. to critically injured

The Marker family opened their door on a recent evening to a woman dressed in purple, with a military attitude to cleanliness. Linda Holmes, who has worked as a technician with LiceDoctors for five years, came straight from her day job at a hospital after she got the call from a dispatcher that the Marker

Researchers have compiled the most comprehensive road map of the protein composition of human lungs, providing a clearer picture of the healthy development of this essential organ that made terrestrial life possible. The study, led by scientists at the Department of Energy’s Pacific Northwest National Laboratory, describes how thousands of molecules are modulated in a

Researchers from the University of Eastern Finland, the University of Exeter, and the University of Bristol carried out the study using data from one of the world’s most extensive ongoing prospective birth cohort studies – the Avon Longitudinal Study of Parents and Children (ALSPAC). Atherosclerotic traits referred to as arterial stiffness seem to independently cause

Melissa Blatzer was determined to get her three children caught up on their routine immunizations on a recent Saturday morning at a walk-in clinic in this Denver suburb. It had been about a year since the kids’ last shots, a delay Blatzer chalked up to the pandemic. Two-year-old Lincoln Blatzer, in his fleece dinosaur pajamas,

Burns are one of the most common injuries suffered by Australians and one of the top causes of death in children under four. While survival rates for burns patients have improved substantially, treating pediatric burns remains challenging, especially with the rise of multi-drug resistant bacteria. Adelaide researchers develop new treatment for serious burns | 7NEWSPlay

Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome. Chromatin is a complex of DNA and protein found in eukaryotic cells; regions of chromatin at key gene regulatory elements appear in open configurations within certain cell nuclei. Precisely delineating these accessible chromatin regions in cells of different

In a recent study published on the preprint server medRxiv*, researchers assess the need for coronavirus disease 2019 (COVID-19) vaccination in children who are 12 years of age or younger. To this end, the researchers compared the clinical characteristics observed in unvaccinated children during the Delta surge (B.1.617.2) in China with that of a vaccinated