Clinical Trials & Research

A novel artificial intelligence score provides a more accurate forecast of the likelihood of patients with suspected or known coronary artery disease dying within 10 years than established scores used by health professionals worldwide. The research is presented today at EuroEcho 2021, a scientific congress of the European Society of Cardiology (ESC). Unlike traditional methods

Okinawa Institute of Science and Technology Graduate University (OIST) and Ryukyu Football Club Co., Ltd. (FC Ryukyu) have today launched a new partnership, aimed at understanding how athletes’ minds behave during team sports. The insights into brain science gained during the project may one day con-tribute to improving the performance of professional athletes in team

Coronaviruses pose a major threat to the global healthcare systems and include zoonotic pathogens such as severe acute respiratory syndrome (SARS-1), severe acute respiratory syndrome coronavirus 2 (SARS-2) and Middle East respiratory syndrome coronavirus (MERS). Coronaviruses enter the host cells using the viral spike (S) protein with the fusion peptide (FP) of the S protein

Most developed countries have enacted mass vaccination schemes to protect their population against coronavirus disease 2019 (COVID-19). However, as the vaccines were developed quickly, not much information is available on the safety or efficacy of these vaccines for those with diseases such as HIV. Study: High seroconversion rate and SARS-CoV-2 Delta neutralization in PLWHIV vaccinated

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein is a trimeric transmembrane protein formed of two subunits that must be cleaved by a host protein to function. The S1 subunit contains a receptor-binding domain (RBD) that binds to angiotensin-converting enzyme 2 (ACE2) to permit viral cell entry. Many variants show mutations in this

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein binds the host cell surface receptor angiotensin-converting enzyme 2 (ACE2). It is a glycosylated protein and is a target for vaccines and therapeutics against the virus. Unraveling the structure of the membrane-bound spike protein will further our understanding of the virulence and pathogenicity of the

Increased inflammation via cytokine storms has led to multiple heart complications in coronavirus disease 2019 (COVID-19) infections. But in order to treat these cardiovascular problems, doctors will need a better understanding of the relationship between cytokine storms and cardiovascular proteins. New research suggests that Th1, Th2, and Th17 inflammatory pathways are involved in the overproduction

According to the WHO, air pollution is the greatest health risk worldwide, accounting for more than 4.2 million deaths annually. In addition, chronic exposure to particulate matter contributes to the risk of cardiovascular and respiratory diseases, and in particular has been associated with high blood pressure, according to a study published in Scientific Reports by

Today, the Centers for Disease Control and Prevention (CDC) is revising the current Global Testing Order to shorten the timeline for required testing for all international air travelers to one day before departure to the United States. This revision strengthens already robust protocols in place for international travel, including requirements for foreign travelers to be

Thought LeadersDr. Rong LuAssistant Professor at the Keck School of MedicineUniversity of Southern CaliforniaIn this interview, News-Medical speaks to Dr. Rong Lu ​​​about her recent research into the development of a new genetic technology for gene expression analysis of cancer cells. Please can you introduce yourself, tell us what inspired your recent research into gene

The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a huge public health emergency. Although several clinical trials have been conducted to identify effective drugs for the treatment of COVID-19, many promising drugs such as hydroxychloroquine, remdesivir, and lopinavir were shown to have little effect

How unresolved grief could haunt children who lost a parent or caregiver to COVIDPlay The number of U.S. deaths from covid-19 has surpassed 778,000. Left behind are tens of thousands of children — some orphaned — after their parents or a grandparent who cared for them died. In this report, co-produced with PBS NewsHour, KHN

Law Enforcement Officers (LEOs), firefighters, and other first responders are at an increased risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, even more so than first-line workers like healthcare professionals. However, the former groups have a relatively low coronavirus disease 2019 (COVID-19) vaccine uptake. Study: High Burden of COVID-19 among Unvaccinated Law

The coronavirus disease (COVID-19) pandemic has demanded a lot from public health authorities in terms of pharmaceutical and non-pharmaceutical interventions to prevent severe disease, hospitalization, and death. While these interventions have proven immensely useful in keeping the general public aware of the consequences and adverse effects of not adhering to existing protocols, the immigrant communities

The appearance of objects can often change. For example, in dim evenings or fog, the contrast of the objects decreases, making it difficult to distinguish them. However, after repeatedly encountering specific objects, the brain can identify them even if they become indistinct. The exact mechanism contributing to the perception of low-contrast familiar objects remains unknown.

To the untrained eye, the loops, kinks and folds in the single strand of RNA that makes up the coronavirus genome look like a jumble of spaghetti or tangled yarn. But to researchers like Amanda Hargrove, a chemistry professor at Duke University, the complex shapes that RNA takes on as it folds upon itself could

Ziath announce Cyclops – a new linear and 2D barcode reader for its popular DataPaq™ Mirage, Cube and Express rack readers. Image Credit: Ziath Ltd Related Stories Cyclops is designed to accurately read linear or 2D codes printed on the edge of tube racks. This enables laboratories to use racks without an integral “97”th code

Patients with existing immunological complications and malignancies have been inferred to be at greater risk of developing severe coronavirus disease 2019 (COVID-19). This holds true for patients with multiple myeloma (MM). Study: Risks of SARS-CoV-2 Breakthrough Infection and Hospitalization in Fully Vaccinated Patients With Multiple Myeloma. Image Credit: creativeneko/ Shutterstock Recent studies have shown a

A Houston Methodist study showed a rapid return of seasonal respiratory viruses after COVID-19 restrictions were relaxed in Texas, demonstrating the effectiveness of masking, distancing and other precautionary measures at stopping the spread of many respiratory illnesses, not just COVID-19. This rise in non-COVID respiratory viruses to pre-pandemic levels came on the heels of Texas

Comorbidities and various risk factors like age, obesity, chronic respiratory disease, and cardiovascular disease affect the severity of coronavirus disease 2019 (COVID-19). In addition, neurological symptoms are one of the common symptoms of COVID-19, which indicates that the virus can potentially infect and replicate in the central nervous system (CNS). However, various pieces of evidence

On June 1, the World Health Organization approved the use of CoronaVac, China’s COVID-19 vaccine, to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. CoronaVac was shown in clinical trials to prevent severe COVID-19 illness along with showing a noticeable safety and immunogenicity profile. In countries such as Chile that have approved CoronaVac, research

Scientists at Scripps Research, Florida have determined the near-atomic-scale structure of an unusual brain-cell receptor called GPR158, which has been linked to depression and anxiety. The structural study reveals both the receptor and its regulating complex, advancing understanding of basic cell receptor biology. It also enables work on potential therapeutics designed to block GPR158 as

Today, CDC Director Rochelle P. Walensky, M.D., M.P.H., endorsed the CDC Advisory Committee on Immunization Practices’ (ACIP) expanded recommendations for booster shots to include all adults ages 18 years and older who received a Pfizer-BioNTech or Moderna vaccine at least six months after their second dose. The Food and Drug Administration’s (FDA) authorization and CDC’s

INTEGRA Biosciences – a leading provider of high quality laboratory equipment – supplies a comprehensive range of liquid handling tools that are ideal for sterile cell biology workflows. Each piece of equipment, from electronic pipettes to robotic pipetting systems and media dispensers, has been expertly designed to fit comfortably under a laminar flow hood to

The coronavirus disease 2019 (COVID-19) outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a sharp rise in deaths and the number of infections worldwide. The pandemic has resulted in the deaths of more than 5.1 million people from more than 254 million infections as of November 18, 2021. Therefore,

A study involving UT Southwestern neurology researchers found lower-quality outcomes for Hispanic ischemic stroke patients who receive endovascular thrombectomies than for comparable white and Black patients. Outcomes were similar between Black and white ischemic stroke patients who receive endovascular thrombectomies, the researchers determined. Ischemic strokes block or narrow an artery leading to the brain. The

A recent study conducted in the United States has revealed that thrombosis with thrombocytopenia syndrome following adenoviral vector-based coronavirus disease 2019 (COVID-19) vaccination is a rare event. However, the condition can cause serious consequences once developed, including hospitalization, intensive care unit (ICU) admission, or even death. The study is currently available on the medRxiv* preprint

We know little about the origin and reservoir of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for the ongoing coronavirus disease 2019 pandemic (COVID-19). However, horseshoe bats tested in Yunnan province, China, have been found to carry the closest relatives of SARS-CoV-2. Now, a new study published in the journal Nature