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“That’s sort of going, ‘Well vanilla didn’t work; we’ll try French vanilla.'” — Gary Sachs, MD, of Massachusetts General Hospital in Boston, on the benefits of adjunctive cariprazine (Vraylar) for patients who have failed on multiple first-line antidepressants. “Here we are, waking up in yet another scenario where we have, in this case, children that
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The 24-hour news cycle is just as important to medicine as it is to politics, finance, or sports. At MedPage Today, new information is posted daily, but keeping up can be a challenge. As an aid for our readers, here is a 10-question quiz based on the news of the week. Topics include long COVID
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Patients who have histologically active ulcerative colitis (UC) with a Mayo endoscopic subscore (MES) of 1 and a history of steroid use may be at increased risk for clinical relapse, according to a new single-center, retrospective analysis. In recent years, treat-to-target approaches in UC have incorporated clinician and patient-reported outcomes, along with endoscopic remission, defined
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Eosinophilic GI diseases (EGIDs) often overlap with other eosinophil-associated diseases (EADs), which leads to greater health care costs, according to an analysis of the U.S. Optum Clinformatics claims database. EADs have gained increased attention in recent years. They include eosinophilic esophagitis (EoE), eosinophilic asthma, bullous pemphigoid, eosinophilic granulomatosis with polyangiitis, eosinophilic gastritis/gastroenteritis (EG/EGE), and a subset of
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Laboratory personnel and those responding to outbreaks of orthopoxviruses, including smallpox and monkeypox, should be vaccinated with Jynneos, finalized recommendations from the CDC’s Advisory Committee on Immunization Practices (ACIP) said on Friday. For healthcare personnel who either administer ACAM2000 or care for patients infected with orthopoxviruses, Jynneos is recommended based on shared clinical decision-making, reported
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Ever since medical experts sounded alarm over the monkeypox outbreak, many have been fearing for another possible pandemic in spite of the COVID-19 global health crisis still going on. To help address the trepidation, public health agencies have decided to release some guidelines on how to stay safe and protected from the monkeypox virus.  The
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SAN DIEGO, California — Race-based recommendations and clinical algorithms may be doing more harm than good, according to a systematic review of databases and guidelines. The study found examples of screening recommendations based on race or ethnicity that were likely misleading since these are social constructs that don’t reflect a patient’s individual risk, said Shazia
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Takotsubo syndrome occurs much more frequently in women than it does in men, but men are much more likely to die from it, according to the results of a new study. In an analysis of almost 2,500 patients with Takotsubo syndrome (TSS) who were enrolled in an international registry, men, who made up just 11%
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Former ‘NSYNC member Lance Bass recently revealed that he has been living with psoriatic arthritis for the past 5 years. In an interview with People magazine, Bass said: “I had symptoms before, but you know, I kind of just dealt with it, not knowing exactly what it was. I was a dancer my whole life,
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Sparring among professional mixed martial arts (MMA) practitioners may have both positive and negative effects on the brain, early research suggests. Investigators found sparring, defined as strategically hitting opponents with kicks, punches, and other strikes during practice sessions, is linked to increased white matter hyperintensities in the brain, pointing to possible vascular damage from repeated
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Researchers stumbled upon a new discovery about the efficacy of the COVID-19 vaccines against long COVID in a new study published this week.  While most studies have reported that the COVID-19 vaccines can hold up strong against hospitalization and death, a new paper published Wednesday in the journal Nature Medicine found that they offer little protection
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[embedded content] In this video, Rohin Francis, MBBS, discusses three stories of controversial figures in the field of regenerative medicine. The following is a partial transcript of this video; note that errors are possible. Francis: The trial of disgraced surgeon Paolo Macchiarini is due to conclude just a couple of days after I’m recording this.
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NEW ORLEANS — People with bipolar disorder – particularly men – show a significantly increased risk of osteoporosis, compared with the general population, but treatment with lithium appears to offer a significant protective effect against the bone disease, according to results from the largest study of its kind. Dr Soren Ostergaard “Our findings emphasize that bone health
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A 56-year-old man has pled guilty to sending death threats to state and federal health officials, including National Institute of Allergy and Infectious Diseases (NIAID) Director Anthony Fauci, MD, and former National Institutes of Health Director Francis Collins, MD. Thomas Patrick
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I am a gopher. See my tiny paws. See them furiously digging and digging and digging. Little puffs of dirt and soil are thrown haphazardly over my little shoulders. My tiny brain was completely absorbed in the digging of that very inconsequential, very little, very specific hole. Tail in the air, head down, no breaks.
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The Centers for Disease Control and Prevention (CDC) issued a warning saying members of the LGBTQ community should take precautionary measures as they are at a higher risk amid the global monkeypox outbreak.  The public health agency said Monday that while everyone is not immune to the monkeypox virus, certain groups of people have greater
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The study covered in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaways Meta-analysis data from eight randomized controlled trials (RCT) showed that transcranial direct-current stimulation (tDCS) treatment for patients with disorders of consciousness (DoC) was more effective at improving behavioral performance compared to controls. Patients
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Regulators and the nation’s largest physician organization took separate steps in recent days to prepare for expected authorization of use of COVID-19 vaccines in children younger than age 6. The US Food and Drug Administration (FDA) on Monday announced its Vaccines
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