The US Food and Drug Administration (FDA) today approved the combination of nivolumab (Opdivo, Bristol-Myers Squibb) plus ipilimumab (Yervoy, Bristol-Myers Squibb) as first-line treatment for patients with metastatic non-small-cell lung cancer (NSCLC) whose tumors express PD-L1 (≥ 1%). Use is limited to patients with no epidermal growth factor receptor or anaplastic lymphoma kinase genomic tumor
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The COVID-19 pandemic has completely changed lives. Schools, universities, offices and public spaces have suddenly shut, along with the imposition of social-distancing and travel restrictions everyone must face. Unemployment, economic downfall, shortage of medical equipment and rise in deaths are currently contributing to widespread distress in the United States. According to a recent study conducted by
Reviewed by Emily Henderson, B.Sc.May 15 2020 People who have experienced maltreatment during childhood are significantly more likely to develop conditions such as heart disease, high blood pressure and type two diabetes in adulthood, a new UK study has found. Childhood maltreatment, which includes any form of physical, sexual or emotional abuse or neglect experienced
Homologous recombination deficiency (HRD) scoring failed to predict PARP inhibitor response in BRCA wild-type ovarian cancer, as women with low scores still appeared to derive benefit, an exploratory analysis of a phase III trial showed. Among 221 patients in the HRD subgroup of VELIA, median progression-free survival (PFS) was 23 months when the investigational PARP
I’d rather hear messages of hope than ticker tapes about death tolls and unnerving and misinformed quotes from people who are in a position to know better and definitely in a position to do better. Not because I am blind to what’s terrible, but because it’s almost impossible to make good things happen if you’re
Vulvovaginal atrophy (atrophic vaginitis) affects roughly a third of breast cancer survivors and negatively impacts their quality of life in multiple ways. The condition can lead to thinning, drying, and inflammation of the vaginal walls and typically occurs when the body produces less estrogen than normal. It can make daily life and activities uncomfortable, and
The COVID-19 outbreak presents unique challenges for those of us living with diabetes. Charlie Kimball, a professional IndyCar driver and father of two and lives with type 1 diabetes. His sport (and job!) is now on hold, and he is home trying to manage his diabetes, eat healthily and stay fit, all the while adjusting
During this virus pandemic, the last thing anyone should worry about is filling and receiving prescriptions, especially if you rely on them to treat serious or chronic conditions. Experts recommend keeping several weeks’ worth of prescriptions you take regularly on hand in the event that you need to stay home, due to illness or shelter-in-place
President Donald Trump speaks about the coronavirus in the Rose Garden of the White House, Friday, May 15, 2020, in Washington. Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, right, and White House coronavirus response coordinator Dr. Deborah Birx listen. Alex Brandon | AP President Donald Trump said the the
A novel telemedicine approach to remotely guide ST-segment elevation myocardial infarction treatment in four Latin American countries screened more than 780,000 patients and resulted in a mortality rate of 5.2%, results from a 1-year, prospective, observational study showed. “We have created a modality where the care of acute MI can be remotely guided,” lead investigator
One of the problems brought by lockdowns and stay-at-home measures is to follow a plant-based lifestyle. You may be one of the people who had no choice but to ditch your eating plans because of very limited food options or chances to do groceries. Getting back to your vegan or vegetarian diet can be difficult
During this virus pandemic, the last thing anyone should worry about is filling and receiving prescriptions, especially if you rely on them to treat serious or chronic conditions. Experts recommend keeping several weeks’ worth of prescriptions you take regularly on hand in the event that you need to stay home, due to illness or shelter-in-place
Print this page KENILWORTH, N.J.–(BUSINESS WIRE) May 13, 2020 –Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced first-time results from a Phase 2 trial evaluating the hypoxia-inducible factor-2 alpha (HIF-2α) inhibitor MK-6482, a novel investigational candidate in Merck’s oncology pipeline, for the treatment of von Hippel-Lindau (VHL) disease-associated clear
Reviewed by Emily Henderson, B.Sc.May 14 2020 While cancer is rare in children, it is, nevertheless, the second most common cause of death during childhood in Switzerland and other European countries. In Switzerland, about 250 children and adolescents under the age of 16 are diagnosed with cancer each year. These diagnoses are recorded in the
Wine, tea and dark chocolate — no, these are not the ingredients to the potion of life, but they might as well be. For one thing, they all contain compounds that can ensure good quality of life for the years to come. Apparently, a new research study has found that tea, wine, dark chocolate and
A polygenic risk score based on analysis of 29 discrete genetic variants linked with abdominal aortic aneurysms appeared better than the current criteria that clinicians use to identify people to screen for this disorder, potentially paving the way for more efficient use of screening resources. Future screening guidelines for abdominal aortic aneurysms (AAA) “should consider
Posted on June 25, 2014 by Greg Harbin Society keeps giving us messages that when we get older, we’re finished. We’re not finished. Every day is a new start. – Billie Jean King, Atria Senior Living’s Well-Being Coach As we age, our quality of life is constantly called into question by society. For those aged 65
Our columnist Grace Victory gets candid about feeling lost in her career. For anyone feeling the same way, she shares her insight to help guide you back on course… As a little girl I always knew what I wanted to be – ‘someone’. I wanted my everyday existence to be full of glitz, glam, and
As data continue to emerge about a multi-system inflammatory disorder in children apparently connected to COVID-19, evidence is growing that this is not your typical Kawasaki disease. In New York, up to 102 children have reportedly developed this inflammatory syndrome, and three children have died from it in the state as of Wednesday. Other cases
In 17 states, the numbers are holding steady, according to an analysis of data from Johns Hopkins University. And in nine states, the numbers of new cases are still rising. Track your state’s cases here But that doesn’t mean it’s time to celebrate and take off face masks in public. As states remove more stay-at-home
Last week, I needed to get some labs drawn. I’m not going to lie, I was terrified and anxious about going back to the hospital. Was I risking exposure to COVID by going in? How could I keep myself safe? I kept myself up much of the night before. Tossing, turning, playing out every possible
Excessive drowsiness during the day could be an indication that something more sinister is happening in the body. It’s a condition called hypersomnolence. It can affect a person’s daily life to the point of being debilitating, as they may fall asleep at work, during an event or meal, or while having a conversation with other
This content originally appeared on Beyond Type 1. Republished with permission. By Erin McShay Sometimes in life, it takes something bad to happen for us to pause and appreciate how good things once were. I used to think of our lives as before and after our Sam was diagnosed with type 1 diabetes. Fast forward
“There is a fear that people are going to die and not get the treatments they need. People are really worried.” – Clare, diagnosed with endometrial cancer in 2013. We caught up with people living with cancer across the country, to find out how isolation due to the pandemic has been affecting them and their
Rick Bright arrives to testify before the House Energy and Commerce Subcommittee on Health on May 14, 2019, in Washington, DC. Greg Nash | AFP | Getty Images Dr. Rick Bright said he’ll never forget the moment when he realized the coronavirus pandemic wreaking havoc in Asia would also become a crisis in the U.S.
Nintendo’s newest offering has been embraced by so many amid the COVID-19 pandemic. Now its creators share what made the game work so much at this point in time. Why Nintendo’s “Animal Crossing: New Horizons” Is Such A Hit When gaming received a significant increase in both sales and player base as a result of
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. The number of COVID-19 deaths cannot be directly compared to the number of seasonal influenza deaths because they are calculated differently, researchers say in a report released today. Whereas COVID-19 death rates are determined from actual counts of people who have
New research has revealed an overwhelming 86% of us have a good relationship with at least one next-door neighbour Whether we’re catching up on the latest must-binge show, doing a little DIY, or unearthing the ancient BBQ we haven’t touched since last summer, we all spend a significant amount of time enjoying our homes. While