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Hyperimmune intravenous immunoglobulin (hIVIG) added to standard of care, including remdesivir (Veklury), did not improve clinical outcomes among hospitalized patients with severe COVID-19, a randomized trial found. People given hIVIG had no better chance of a better clinical outcome at day 7 compared with those assigned placebo (adjusted OR 1.06, 95% CI 0.77-1.45), reported Mark
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The newly approved insomnia drug daridorexant (Quviviq) improves sleep onset in adults, new phase 3 data suggest.   In the first of two studies, a 50-mg dose of daridorexant was associated with a reduction in latency to persistent sleep (LPS) of 11.7 minutes at month 3 vs placebo. The drug was also associated with improved
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[embedded content] We all know that some doctors make more money than others, but are they actually making more money per hour? Or are they just working more hours? Let’s dive into the data and find out. When discussing which specialties make the most money, the conversation usually starts and ends with annual salaries. Although
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Instagram pulled more than 30 ads running by mental health startup Cerebral for violating policies of using certain types of imagery to promote healthcare products. (Forbes) Only about a fifth of real-world patients with schizophrenia were represented in randomized clinical trials (RCTs) — and this slim selection of patients tended to have better outcomes. “RCTs
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A new statement from the US Preventive Services Task Force (USPSTF) concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for atrial fibrillation (AF) in asymptomatic adults. The guidance is similar to the Task Force’s 2018 statement on screening for AF with electrocardiography (ECG) in asymptomatic adults 65
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Testing people with COVID symptoms has been a pillar of the UK’s pandemic response, reducing transmission by identifying and isolating those with the virus. But to be effective, it relies on people with symptoms getting tested, which raises an obvious question: what proportion of symptomatic people actually take a test? The ZOE COVID Study, which
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. New York state education officials told school administrators to continue enforcing the state’s mask mandate for students and teachers Tuesday despite a judge’s ruling overturning it, causing confusion as some districts rushed to make masks optional. The Education Department said the
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Medical laboratory professionals form the backbone of health care and the public health system. They conduct some 13 billion laboratory medicine tests annually in the U.S. As of January 2022, these individuals had also performed more than 860 million COVID-19 tests and counting during the pandemic. Why should anyone care? Laboratory testing is the single
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The COVID-19 pandemic is far from over if the World Health Organization head’s latest statement is to be believed. Tedros Adhanom Ghebreyesus, the organization’s director-general, said that instead of assuming that the global health crisis is coming to a end, nations should stay vigilant and focused on the challenges that could surface next.  Approaching The End?
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A 35-year-old man presented to the emergency department with extreme pain in his penis and scrotum. He explained that his symptoms started after he injected cocaine into the dorsal vein of his penis 3 days previously, and the pain has been intensifying. He told clinicians that immediately after injecting the cocaine, he experienced severe pain
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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. A small study may help explain the cause of “brain fog,” the lingering mental confusion reported in some people who’ve had COVID. Researchers at the University of California, San Francisco, found abnormalities in the cerebrospinal fluid — the clear, colorless liquid
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There’s now scientific data on the potential impairment of fertility in men infected with SARS-CoV-2.  A new study funded by the National Institutes of Health (NIH) found that a man’s fertility could be negatively affected by a COVID-19 infection.  Researchers who worked on the study published Thursday in the American Journal of Epidemiology reported that
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Postacute COVID syndrome (PACS), an ongoing inflammatory state following infection with SARS-CoV-2, is associated with greater risk of metabolic-associated fatty liver disease (MAFLD), according to an analysis of patients at a single clinic in Canada published in Open Forum Infectious Diseases. MAFLD, also known as nonalcoholic fatty liver disease (NAFLD), is considered an indicator of
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The survival rate following a sports-related cardiac arrest (SrSCA) almost tripled over a recent 12-year period, due in large part to increased bystander use of automated external defibrillators (AEDs) and cardiopulmonary resuscitation (CPR), results of a new study from France suggest. Lead author Nicole Karam, MD, PhD, associate professor in interventional cardiology, University of Paris, credits
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The 24-hour news cycle is just as important to medicine as it is to politics, finance, or sports. At MedPage Today, new information is posted daily, but keeping up can be a challenge. As an aid for our readers, here is a 10-question quiz based on the news of the week. Topics include adverse events
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The US Food and Drug Administration (FDA) today approved risankizumab-rzaa (Skyrizi) for a second indication — treating adults with active psoriatic arthritis (PsA) — making it the second anti-interleukin 23 monoclonal antibody available to treat PsA, according to an announcement from manufacturer AbbVie. The agency previously approved risankizumab in April 2019 for adults with moderate-to-severe
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