New research provides strong support for current advice to “sit less and move more” for better health. In a study that tracked more than 100,000 adults from 21 countries for more than 10 years, more time spent sitting during the day was associated with increased risk for early death and heart disease. The combination of
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An FDA advisory panel rejected pimavanserin (Nuplazid) for the treatment of hallucinations and delusions in patients with Alzheimer’s disease psychosis on Friday. In a vote of 9-3, the Psychopharmacologic Drugs Advisory Committee decided against recommending the drug for approval for these patients, citing a slew of shortcomings in supporting trial data. This could have been
The Centers for Disease Control and Prevention (CDC) has issued a set of guidelines for sexually active people amid the monkeypox outbreak. The public health agency took the initiative to inform the public how safer sex practices could help prevent the spread of the virus. “While we work to contain the current outbreak and study
A US Food and Drug Administration (FDA) advisory panel has rejected the atypical antipsychotic pimavanserin (Nuplazid, Acadia Pharmaceuticals) for the treatment of Alzheimer’s disease psychosis (ADP). In a 9-3 vote, the Psychopharmacologic Drugs Advisory Committee (PDAC) found that the drug’s manufacturer failed to offer convincing evidence of its efficacy in patients with ADP. Today’s rejection
The Omicron variant of coronavirus is less likely to cause long COVID than previous variants, according to the first peer-reviewed study of its kind from the United Kingdom. Researchers at King’s College London, using data from the ZOE COVID Symptom study app, found the odds of developing long COVID after infection were 20% to 50%
British Columbia will be the first Canadian province to allow adult possession of small amounts of illegal drugs. Starting in January 2023 and continuing through January 2026, it will no longer be a criminal offense to possess up to 2.5 mg of crack or powder cocaine, MDMA (3,4 methylenedioxymethamphetamine), methamphetamine, or opioids (including heroin, morphine,
Ever since the threat of an avian flu pandemic in 2006, governments, hospitals, and professional associations have been preparing for the next “big one.” New York State was a leader in pandemic preparation, having developed its Ventilator Allocation Guidelines in 2007, with updates in 2015. And yet, when the COVID tsunami hit New York City
The U.S. Environmental Protection Agency on Wednesday released new warnings for synthetic pollutants in drinking water known as “forever chemicals” saying the toxins can still be harmful even at levels so low they are not detectable. The family of toxic chemicals known as per-and polyfluoroalkyl substances, or PFAS, have been used for decades in household
June 16, 2022 — What would you do if you believed you had a serious health issue, but the best way to find out for sure might kill you? That’s the reality for patients who wish to confirm or rule out a food allergy, says Sindy Tang, PhD, an associate professor of mechanical engineering at
The novel coronavirus may also be the culprit behind the mysterious cases of hepatitis in children in recent months. A new study by Israeli researchers presented a theory that long COVID could be why some children developed hepatitis amid the pandemic. In their study published in the Journal of Pediatric Gastroenterology and Nutrition, the researchers
It all began with the question, “Has your butt been getting enough attention?” Though that may seem unorthodox, it led researchers to discovering a treatment that may help prevent anal cancer in people with HIV/AIDS. It’s still featured on their study’s website, with this further explanation: “You get your viral load checked, your T-cell count
Treating precancerous anal lesions in people with HIV reduced their risk of developing anal cancer by more than half compared with active monitoring, according to results from the ANCHOR study. In the randomized phase III trial of more than 4,500 individuals with anal high-grade squamous intraepithelial lesions (HSIL), nine of those assigned to treatment with
Having kids do household chores may have more benefits beyond helping keep the home in order. It may also aid in the development of kids’ executive functions, a study has found. In many households, family members each have their own chores to fulfill on a daily basis, and even children have their own tasks to complete.
Heads up, parents: Fisher-Price and the Consumer Product Safety Commission (CPSC) said this week that between 2009 and 2022, at least 13 infants died after falling asleep in the company’s rockers. The deaths were linked to the Fisher-Price Infant-to-Toddler Rockers and the Newborn-to-Toddler Rockers, according to a Tuesday statement from the CPSC and Fisher-Price. The
Looks like too much exposure to ultraviolet rays is not the only threat when preventing skin cancer. A novel study has reported a surprising link between the condition and fish consumption. Research has found that eating fish could likely increase the likelihood of skin cancer. And it’s not just the mild form of the condition
The study covered in this summary was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaways Whereas an elevated neutrophil-to-lymphocyte ratio has been previously associated with increased risk for mortality in patients with cancer, the current study suggests it is also a predictor of risk for cardiotoxicity from anthracycline
In the mid-16th century, surgical education was that of a true apprenticeship. The student learned through direct observership and imitation of a skilled, elder surgeon. It wasn’t until the beginning of the 20th century that surgical education evolved into a formalized and structured program. William Osler, MD, CM, introduced the concepts of specialty clerkships and
More than 14 percent of the world’s population has had Lyme disease, the most common tick-borne illness, according to a major review of the available research published on Tuesday. Central Europe had the highest rate of infection with 20 percent, while men over the age of 50 living in rural areas were most at risk,
The US Food and Drug Administration’s (FDA) vaccine advisory panel today unanimously recommended granting emergency use authorization (EUA) for Moderna’s COVID-19 vaccine for ages 6-17 years. The Moderna vaccine is currently fully approved for adults 18 years and older. Two votes were taken by the Vaccines and Related Biological Products Advisory Committee (VRBPAC) — one
Stresses related to the COVID-19 pandemic affected women’s ovulation, researchers have found. The “experiment of nature” reportedly demonstrated how stressors can affect women’s fertility. The COVID-19 pandemic certainly caused major disruptions in many people’s lives. It also led many people to experience quite a lot of stress, and women certainly weren’t exempted from this. For
“Have you ever had a nightmare when you’re running to class and when you get there you have no pants on? That’s how I feel today. Naked. No Powerpoint slides to hide behind.” This was Neal J. Meropol, MD, standing alone on the stage addressing the audience at ASCO Voices, a regular storytelling event held
Triptans were associated with fewer major adverse cardiovascular events (MACE) in acute migraine patients with a history of cardiovascular conditions compared with nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids/butalbital, patient registry data showed. Among people with acute migraine and at least one baseline cardiovascular condition, MACE occurred with 0.90% of triptan prescriptions, 4.52% of opioid/butalbital prescriptions,
Ventricular arrhythmias more commonly occur on days when there are higher levels of air pollution, especially with fine particulate matter (PM), a new study suggests. Investigators studied the relationship between air pollution and ventricular arrhythmias in Piacenza, Italy by examining 5-year data on patients who received an implantable cardioverter defibrillator (ICD). They found a significant
Those who consume too much fructose may be at risk of developing non-alcoholic fatty liver disease (NAFLD), a team of researchers has found. Fructose, also called “fruit sugar,” is a natural sugar that’s one of the three common natural monosaccharides, along with glucose and galactose. As the name implies, it is present in almost all fruits, though it
People younger than 50 years with metabolic syndrome or obesity may need more effective prevention measures to help reduce their risk for colorectal cancer (CRC), new data suggest. Metabolic syndrome and obesity are positively linked with colorectal cancer before age 50, with rates similar to those in people diagnosed with CRC after age 50, reports
Zavegepant, an investigational nasal spray formulation of a small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist, met its co-primary endpoints in a phase III randomized placebo-controlled trial of acute migraine. On both primary endpoints — 2-hour pain freedom (23.6% vs 14.9%, P<0.0001) and 2-hour freedom from most bothersome symptom (39.6% vs 31.1%, P=0.0012) — zavegepant was
ATLANTA — Goal-directed glycemic management — which may include new technologies for glucose monitoring — for non-critically ill hospitalized patients who have diabetes or newly recognized hyperglycemia can improve outcomes, according to a new practice guideline from the Endocrine Society. Even though roughly 35% of hospitalized patients have diabetes or newly discovered hyperglycemia, there
A newly approved medication for diabetes has shown promise with its ability to help people lose weight on top of treating the medical condition. The U.S. Food and Drug Administration recently approved Mounjaro (tirzepatide) for the treatment of adults suffering type 2 diabetes. The drug got the approval after showing its efficiency in improving blood
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