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Adults should be tested for hepatitis B virus (HBV) at least once in their lifetime, according to updated guidelines from the Centers for Disease Control and Prevention (CDC). This is the first update to HBV screening guidelines since 2008, the agency said. “Risk-based testing alone has not identified most persons living with chronic HBV infection and
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A very rare intraventricular fetus-in-fetu was surgically removed from a 1-year-old girl with motor delay and an enlarged head circumference, a report from China showed. The fetiform mass was a malformed monochorionic diamniotic twin, reported Chunde Li, MD, of Beijing Tiantan Hospital, and co-authors in Neurology. Genetic sequencing showed identical single-nucleotide variants in the host
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Already commonly used in combination for the treatment of pulmonary arterial hypertension (PAH), macitentan and tadalafil are safe and effective in a fixed-dose combination even as first-line therapy, according to a randomized multicenter comparative trial. The fixed-dose combination “led to a highly significant and marked improvement in pulmonary vascular resistance when compared to macitentan and
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Scientists seem to have done the impossible. They have created mice with two biological fathers. The revolutionary research could open the way for new fertility treatments in the future, including reproduction in same-sex couples. “This is the first case of making robust mammal oocytes from male cells,” said Katsuhiko Hayashi, who led the research team at Kyushu
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The television series “The Last of Us” describes a human pandemic with a mind controlling cordyceps fungus. When asked whether a COVID-19 pandemic with a pathogenic fungus is possible, my answer has generally been some variation of “yes, but it’s unlikely.” Cordyceps fungi turn ants into zombies, establishing the precedent that this group of organisms
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Individuals with a history of depressive symptoms have a 46% higher risk for stroke than those with no depression history, new research suggests. Data from the international INTERSTROKE study also showed that those with depressive symptoms before a stroke had worse outcomes, including a significantly higher mortality rate in the first month after a stroke.
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The Food and Drug Administration (FDA) issued several recall notices for two brands of eyedrops that may not be sterile and could lead to extensive vision problems and serious injury. The recall affects certain eyedrops distributed by Pharmedica and Apotex, and follows a February recall which was linked to a multi-state outbreak of drug-resistant infections. That outbreak
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Sales of a bestselling health book by a high-profile University of Southern California oncologist have been suspended because of dozens of instances of plagiarism. The Los Angeles Times reported earlier this week that it identified at least 95 instances of plagiarism by author David B. Agus, MD, in The Book of Animal Secrets: Nature’s Lessons
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Two US Drug Enforcement Administration (DEA) proposals on how telehealth can be used going forward to prescribe controlled substances are drawing criticism from mental health and addiction treatment specialists. The proposed rules — one for Schedule III-V substances, and the other for buprenorphine — are due to go into effect on May 11, when the
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Scientists have developed an innovative headphone that can clear out earwax efficiently without creating a mess. The headphone-shaped cleaning device is called OtoSet Ear Cleaning System, and is the product of the Seattle-based medical startup SafKan Health. Otoset is claimed by the startup to be the first FDA-approved ear-cleaning device for removing mild to severe
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Codon-specific KRAS mutations are predictive of an overall survival (OS) benefit for metastatic colorectal cancer (mCRC) patients treated with trifluridine-tipiracil (FTD/TPI; Lonsurf), according to a genomics-based analysis. After identifying biomarkers of resistance and validating the findings in a real-world dataset, researchers showed that patients with KRAS G12-mutant tumors in the phase III RECOURSE trial achieved
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COPENHAGEN — Children and young adults with inflammatory bowel disease (IBD) are about 2.5 times more likely to develop posttraumatic stress disorder (PTSD), almost twice as likely to report an eating disorder, and 1.5 times more likely to engage in self-harm, a new UK study suggests. The retrospective, observational study of young people with IBD
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NEW ORLEANS – EHR-embedded alerts that a patient with heart failure with reduced ejection fraction (HFrEF) is a great candidate for treatment with a mineralocorticoid receptor antagonist (MRA) more than doubled prescribing of this “pillar” class for HFrEF, compared with control practices that used usual care and no alerts. That’s according to results of BETTER CARE-HF,
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Sometimes, employees feel dissatisfied in their workplace and it can affect their productivity, as well as their mental and physical health. A new study looks at a previously ignored factor that has a significant effect on employees’ mental health. The study, published in the Journal of Research in Personality, found that office space designs have a bearing on
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NEW ORLEANS – Immediate complete revascularization was non-inferior to staged complete revascularization in patients who presented with acute coronary syndrome (ACS) and multivessel disease, according to BIOVASC trial findings. In the prospective, open-label study, the composite primary outcome occurred in 7.6% of 764 patients in the immediate complete revascularization group and in 9.4% of 761
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Patients with degenerative mitral valve (MV) regurgitation that calls for surgery may, for the most part, safely choose either a standard procedure requiring a midline sternotomy  or one performed through a mini-thoracotomy, suggests a randomized comparison of the two techniques. Still, the minimally invasive approach showed some advantages in the study. Patients’ quality of recovery
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NEW ORLEANS – In the first pivotal randomized, controlled trial of a transcatheter device for the repair of severe tricuspid regurgitation, a large reduction in valve dysfunction was associated with substantial improvement in quality of life (QOL) persisting out of 1 year of follow-up, according to results of the TRILUMINATE trial. Based on the low procedural
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NEW ORLEANS — Transcatheter edge-to-edge repair (TEER) of severely regurgitant tricuspid valves improved outcomes, largely in terms of quality of life, the TRILUMINATE Pivotal trial showed. Compared with medical therapy alone, the percutaneous placement of an investigational TriClip device to hold the leaflets together was favored in a Bayesian analysis with a win ratio of
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